Long-Lasting Desynchronization of Plastic Neuronal Networks by Double-Random Coordinated Reset Stimulation

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• Long-Lasting Desynchronization of Plastic Neuronal Networks by Double-Random Coordinated Reset Stimulation March 17, 2023 Front Netw Physiol. 2022 Apr 19;2:864859. doi: 10.3389/fnetp.2022.864859. eCollection 2022.ABSTRACTHypersynchrony of neuronal activity is associated with several neurological disorders, including essential tremor and Parkinson's disease (PD). Chronic high-frequency deep brain stimulation (HF DBS) is the standard of care for medically refractory PD. Symptoms may effectively be suppressed by HF DBS, but return shortly after cessation of stimulation. Coordinated reset (CR)…
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• Long-Lasting Desynchronization of Plastic Neuronal Networks by Double-Random Coordinated Reset Stimulation March 17, 2023 Front Netw Physiol. 2022 Apr 19;2:864859. doi: 10.3389/fnetp.2022.864859. eCollection 2022.ABSTRACTHypersynchrony of neuronal activity is associated with several neurological disorders, including essential tremor and Parkinson's disease (PD). Chronic high-frequency deep brain stimulation (HF DBS) is the standard of care for medically refractory PD. Symptoms may effectively be suppressed by HF DBS, but return shortly after cessation of stimulation. Coordinated reset (CR)…
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• Long-Lasting Desynchronization Effects of Coordinated Reset Stimulation Improved by Random Jitters October 11, 2021 Front Physiol. 2021 Sep 24;12:719680. doi: 10.3389/fphys.2021.719680. eCollection 2021.ABSTRACTAbnormally strong synchronized activity is related to several neurological disorders, including essential tremor, epilepsy, and Parkinson's disease. Chronic high-frequency deep brain stimulation (HF DBS) is an established treatment for advanced Parkinson's disease. To reduce the delivered integral electrical current, novel theory-based stimulation techniques such as coordinated reset (CR) stimulation directly counteract the…
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