Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson’s Disease

Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson’s Disease
Mov Disord. 2021 May 4. doi: 10.1002/mds.28608. Online ahead of print.ABSTRACTBACKGROUND: Cerebrospinal fluid (CSF) levels of monoamine metabolites may represent biomarkers of Parkinson's disease (PD).OBJECTIVE: The aim of this study was quantification of multiple metabolites in CSF from PD versus healthy control subjects (HCs), including longitudinal analysis.METHODS: Absolute levels of multiple monoamine metabolites in CSF were quantified by liquid chromatography ... read more
Source: PubMedPublished on 2021-05-04By Thomas Kremer