Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease

Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease
NPJ Parkinsons Dis. 2022 Jun 22;8(1):79. doi: 10.1038/s41531-022-00341-8.ABSTRACTThe prevailing network perspective of Parkinson's disease (PD) emerges not least from the ascending neuropathology traceable in histological studies. However, whether longitudinal in vivo correlates of network degeneration in PD can be observed remains unresolved. Here, we applied a trimodal imaging protocol combining 18F-fluorodeoxyglucose (FDG)- and 18F-fluoro-L-Dopa- (FDOPA)-PET with resting-state functional MRI to ... read more
Source: PubMedPublished on 2022-06-22By Kenan Steidel