Loss of Function in Key Genes Doesn’t Change Parkinson’s Risk, Study Finds

Loss of Function in Key Genes Doesn’t Change Parkinson’s Risk, Study Finds
Loss or inactivation of a single gene copy of LRRK1 or LRRK2 — LRRK mutations being a common genetic cause of Parkinson’s disease — neither increases the risk nor protects against the disease, a new study showed. These findings also support the use of kinase inhibitors targeting mutant LRRK2 as a therapeutic option for the disease. The study, “Frequency of Loss ... read more
Source: Parkinson’s News TodayPublished on 2018-08-03By Joana Carvalho