Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements

Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements
Mov Disord. 2021 Feb 22. doi: 10.1002/mds.28532. Online ahead of print.ABSTRACTBACKGROUND: In movement disorders such as Parkinson's disease (PD), cholinergic signaling is disrupted by the loss of basal forebrain cholinergic neurons, as well as aberrant activity in striatal cholinergic interneurons (ChIs). Several lines of evidence suggest that gait imbalance, a key disabling symptom of PD, may be driven by alterations ... read more
Source: PubMedPublished on 2021-02-22By Martin Sarter