Mass spectrometry methods for analysis of extracellular matrix components in neurological diseases

Mass spectrometry methods for analysis of extracellular matrix components in neurological diseases
Mass Spectrom Rev. 2022 Jun 20:e21792. doi: 10.1002/mas.21792. Online ahead of print.ABSTRACTThe brain extracellular matrix (ECM) is a highly glycosylated environment and plays important roles in many processes including cell communication, growth factor binding, and scaffolding. The formation of structures such as perineuronal nets (PNNs) is critical in neuroprotection and neural plasticity, and the formation of molecular networks is dependent ... read more
Source: PubMedPublished on 2022-06-20By Margaret Downs