Methylation of alpha-synuclein in a Sudanese cohort

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• Methylation of alpha-synuclein in a Sudanese cohort June 21, 2022 Parkinsonism Relat Disord. 2022 Jun 4;101:6-8. doi: 10.1016/j.parkreldis.2022.05.009. Online ahead of print.ABSTRACTBACKGROUND: Several studies suggested a significant role of epigenetic changes, including alterations in miRNA, histone modifications, and DNA methylation of α-synuclein (SNCA) in Parkinson's disease (PD) pathogenicity. As of yet, only very few studies have been carried out in this field in Africa and none in Sudan.MATERIALS AND METHODS:…
• Methylation of alpha-synuclein in a Sudanese cohort June 21, 2022 Parkinsonism Relat Disord. 2022 Jun 4;101:6-8. doi: 10.1016/j.parkreldis.2022.05.009. Online ahead of print.ABSTRACTBACKGROUND: Several studies suggested a significant role of epigenetic changes, including alterations in miRNA, histone modifications, and DNA methylation of α-synuclein (SNCA) in Parkinson's disease (PD) pathogenicity. As of yet, only very few studies have been carried out in this field in Africa and none in Sudan.MATERIALS AND METHODS:…
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