Methylation of alpha-synuclein in a Sudanese cohort

Methylation of alpha-synuclein in a Sudanese cohort
Parkinsonism Relat Disord. 2022 Jun 4;101:6-8. doi: 10.1016/j.parkreldis.2022.05.009. Online ahead of print.ABSTRACTBACKGROUND: Several studies suggested a significant role of epigenetic changes, including alterations in miRNA, histone modifications, and DNA methylation of α-synuclein (SNCA) in Parkinson's disease (PD) pathogenicity. As of yet, only very few studies have been carried out in this field in Africa and none in Sudan.MATERIALS AND METHODS: ... read more
Source: PubMedPublished on 2022-06-21By Yousuf Bakhit