Meynert nucleus-related cortical thinning in Parkinson’s disease with mild cognitive impairment

Meynert nucleus-related cortical thinning in Parkinson’s disease with mild cognitive impairment
Quant Imaging Med Surg. 2021 Apr;11(4):1554-1566. doi: 10.21037/qims-20-444.ABSTRACTBACKGROUND: Cognitive impairment in Parkinson's disease (PD) involves the cholinergic system and cholinergic neurons, especially the nucleus basalis of Meynert (NBM/Ch4) located in the basal forebrain (BF). We analyzed associations between NBM/Ch4 volume and cortical thickness to determine whether the NBM/Ch4-innervated neocortex shows parallel atrophy with the NBM/Ch4 as disease progresses in PD ... read more
Source: PubMedPublished on 2021-04-05By Siming Rong