Midbrain atrophy in patients with presymptomatic progressive supranuclear palsy-Richardson’s syndrome.

Related Articles:

• Forward and backward walking in Parkinson disease: A factor analysis. August 23, 2019 Forward and backward walking in Parkinson disease: A factor analysis. Gait Posture. 2019 Aug 12;74:14-19 Authors: Gilmore G, Gouelle A, Adamson MB, Pieterman M, Jog M Abstract BACKGROUND: Forward and backward walking are both impaired in Parkinson disease (PD). In this study, an exploratory factor analysis was performed to investigate the relationship between forward and backward walking in PD. RESEARCH…
• Neurogenic orthostatic hypotension impairs information processing speed and attention. September 19, 2019 Related ArticlesNeurogenic orthostatic hypotension impairs information processing speed and attention. Physiol Behav. 2019 Sep 14;:112682 Authors: Robinson L, Kimpinski K Abstract Neurogenic orthostatic hypotension (NOH) is characterized by a drop in systolic blood pressure (SBP) ≥20 mmHg or diastolic blood pressure (DBP) ≥10 mmHg within three minutes of upright posture. NOH is common in the elderly population. This group of individuals is…
• Combining quantitative susceptibility mapping to the morphometric index in differentiating between progressive supranuclear palsy and Parkinson's disease. October 22, 2019 Combining quantitative susceptibility mapping to the morphometric index in differentiating between progressive supranuclear palsy and Parkinson's disease. J Neurol Sci. 2019 Aug 31;406:116443 Authors: Azuma M, Hirai T, Nakaura T, Kitajima M, Yamashita S, Hashimoto M, Yamada K, Uetani H, Yamashita Y, Wang Y Abstract PURPOSE: To determine whether the susceptibility value in the deep gray matter obtained by quantitative…
• Long-term trends in myocardial sympathetic innervation and function in synucleinopathies. October 18, 2019 Long-term trends in myocardial sympathetic innervation and function in synucleinopathies. Parkinsonism Relat Disord. 2019 Sep 16;67:27-33 Authors: Lamotte G, Holmes C, Wu T, Goldstein DS Abstract INTRODUCTION: Parkinson disease (PD), pure autonomic failure (PAF), and multiple system atrophy (MSA) are characterized by intra-cerebral deposition of the protein alpha-synuclein and are termed synucleinopathies. Lewy body synucleinopathies involve decreased cardiac sympathetic innervation…
• Striatal DAT and extrastriatal SERT binding in early-stage Parkinson's disease and dementia with Lewy bodies, compared with healthy controls: An 123I-FP-CIT SPECT study. March 19, 2019 Related ArticlesStriatal DAT and extrastriatal SERT binding in early-stage Parkinson's disease and dementia with Lewy bodies, compared with healthy controls: An 123I-FP-CIT SPECT study. Neuroimage Clin. 2019 Mar 12;22:101755 Authors: Joling M, Vriend C, Raijmakers PGHM, van der Zande JJ, Lemstra AW, Berendse HW, Booij J, van den Heuvel OA Abstract Parkinson's disease (PD) and dementia with Lewy bodies (DLB)…
• The Association between Prefrontal Cortex Activity and Turning Behavior in People with and without Freezing of Gait. July 23, 2019 The Association between Prefrontal Cortex Activity and Turning Behavior in People with and without Freezing of Gait. Neuroscience. 2019 Jul 19;: Authors: Belluscio V, Stuart S, Bergamini E, Vannozzi G, Mancini M Abstract Turning elicits Freezing of Gait (FoG) episodes in people with Parkinson's disease (PD) and is thought to require higher cortical control compared to straight ahead gait. Functional…
• Automated and objective measures of gait dynamics in camptocormia Parkinson's Disease subthalamic deep brain stimulation. October 13, 2019 Automated and objective measures of gait dynamics in camptocormia Parkinson's Disease subthalamic deep brain stimulation. Clin Neurol Neurosurg. 2019 Sep 26;186:105537 Authors: Soares C, Vilas-Boas MDC, Lopes EM, Choupina H, Soares-Dos-Reis R, Fitas D, Cunha JPS, Monteiro P, Linhares P, Rosas MJ Abstract OBJECTIVE: Axial motor features are common in Parkinson's disease (PD). These include gait impairment and postural abnormalities,…
• Frequency and characteristic features of REM sleep without atonia. August 12, 2019 Frequency and characteristic features of REM sleep without atonia. Clin Neurophysiol. 2019 Jul 27;130(10):1825-1832 Authors: Dijkstra F, Viaene M, Crosiers D, De Volder I, Cras P Abstract OBJECTIVES: Isolated REM sleep without atonia (iRSWA) is regarded as prodromal phase of REM sleep behavior disorder (RBD) and synucleinopathies. Other factors, however, have also been described to cause RSWA, including sleep apnea,…
• Quantifying physical activity in early Parkinson disease using a commercial activity monitor. August 20, 2019 Related ArticlesQuantifying physical activity in early Parkinson disease using a commercial activity monitor. Parkinsonism Relat Disord. 2019 Aug 03;: Authors: Pradhan S, Kelly VE Abstract INTRODUCTION: Physical inactivity in Parkinson disease (PD) has an impact on motor and non-motor symptoms of the disease. It is unclear whether this decline in physical activity occurs early in the disease, in addition to…
• Quantitative magnetization transfer imaging of the human locus coeruleus. June 25, 2019 Quantitative magnetization transfer imaging of the human locus coeruleus. Neuroimage. 2019 Jun 21;: Authors: Trujillo P, Petersen KJ, Cronin MJ, Lin YC, Kang H, Donahue MJ, Smith SA, Claassena DO Abstract The locus coeruleus (LC) is the major origin of norepinephrine in the central nervous system, and is subject to age-related and neurodegenerative changes, especially in disorders such as Parkinson's…
• Speech difficulties in early de novo patients with Parkinson's disease. May 13, 2019 Speech difficulties in early de novo patients with Parkinson's disease. Parkinsonism Relat Disord. 2019 May 07;: Authors: Polychronis S, Niccolini F, Pagano G, Yousaf T, Politis M Abstract INTRODUCTION: Speech difficulties are a common debilitating feature of Parkinson's disease and we aimed to investigate whether speech difficulties are associated with striatal dopaminergic deficits and faster disease progression. METHODS: Using the…
• Preclinical signs of Parkinson's disease: A possible association of Parkinson's disease with skin and hair features. May 16, 2019 Preclinical signs of Parkinson's disease: A possible association of Parkinson's disease with skin and hair features. Med Hypotheses. 2019 Jun;127:100-104 Authors: Jucevičiūtė N, Banaitytė I, Vaitkus A, Balnytė R Abstract Parkinson's disease (PD) is a neurodegenerative disorder, characterized by loss of dopaminergic neuromelanin containing neurons in the substantia nigra. Peripheral melanin, found in skin and hair, and neuromelanin appear to…
• Predictors of Pisa syndrome in Chinese patients with Parkinson's disease: A prospective study. October 22, 2019 Predictors of Pisa syndrome in Chinese patients with Parkinson's disease: A prospective study. Parkinsonism Relat Disord. 2019 Oct 13;69:1-6 Authors: Liu K, Ou R, Hou Y, Wei Q, Cao B, Song W, Zhao B, Shang H Abstract INTRODUCTION: Pisa Syndrome (PS) is a disabling complication in Parkinson's disease (PD) with unclear pathogenesis, yet studies on the longitudinal observation of PS…
• Neuregulin1β improves both spatial and associative learning and memory in Alzheimer model of rats possibly through signaling pathways other than Erk1/2. September 17, 2019 Related ArticlesNeuregulin1β improves both spatial and associative learning and memory in Alzheimer model of rats possibly through signaling pathways other than Erk1/2. Neuropeptides. 2019 Sep 07;:101963 Authors: Jalilzad M, Jafari A, Babaei P Abstract BACKGROUND: Neuregulin-1β (NRG1 β) is associated with various neurological disorders such as schizophrenia, depression and Parkinson's disease. However, its role in Alzheimer's (AD) has not been…
• Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester. June 8, 2019 Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester. Bioorg Chem. 2019 May 28;89:103017 Authors: Boztas M, Taslimi P, Yavari MA, Gulcin I, Sahin E, Menzek A Abstract Trans-(1R*,2R*,3R*)-Ethyl 2-(3,4-dimethoxyphenyl)-3-methylcyclopropane-1-carboxylate (6) and its cis isomer 7 were obtained from the reaction of the methyl isoeugenol (5) with ethyl diazoacetate. The reduction and bromination…
• Anemia in men and increased Parkinson's disease risk: A population-based large scale cohort study. March 30, 2019 Related ArticlesAnemia in men and increased Parkinson's disease risk: A population-based large scale cohort study. Parkinsonism Relat Disord. 2019 Mar 23;: Authors: Rozani V, Giladi N, Gurevich T, El-Ad B, Tsamir J, Hemo B, Peretz C Abstract OBJECTIVE: To evaluate the association between anemia and Parkinson's disease risk (PD) in men and women. METHODS: A population-based cohort of 474,129 individuals…
• Haptic perception of verticality correlates with postural and balance deficits in patients with Parkinson's disease. July 8, 2019 Related ArticlesHaptic perception of verticality correlates with postural and balance deficits in patients with Parkinson's disease. Parkinsonism Relat Disord. 2019 Jul 02;: Authors: Mori L, Putzolu M, Bonassi G, Galeoto G, Mezzarobba S, Trompetto C, Avanzino L, Marchese R, Abbruzzese G, Pelosin E Abstract INTRODUCTION: Perception of verticality is fundamental for postural stability that is often impaired in patients with…
• The effect of levodopa on saccades - Oxford Quantification in Parkinsonism study. October 18, 2019 The effect of levodopa on saccades - Oxford Quantification in Parkinsonism study. Parkinsonism Relat Disord. 2019 Sep 27;68:49-56 Authors: Lu Z, Buchanan T, Kennard C, FitzGerald JJ, Antoniades CA Abstract OBJECTIVES: The evaluation of novel disease modifying drugs requires biomarkers that are simultaneously sensitive to disease state but resistant to the effects of background symptomatic treatment. Saccadic eye movement parameters…
• Deterioration of postural deformity in Parkinson's disease patients with punding and hobbyism. August 12, 2019 Deterioration of postural deformity in Parkinson's disease patients with punding and hobbyism. J Clin Neurosci. 2019 Aug 07;: Authors: Aoki R, Shiraishi M, Mikami K, Kamo T Abstract This study aimed to examine whether worsening of postural deformities is seen in Parkinson's disease (PD) patients who exhibit the behavioral disorders punding or hobbyism (P-H), which involve maintaining the same poor…
• Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease. October 25, 2019 Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease. Exp Gerontol. 2019 Oct 21;:110740 Authors: Cherup NP, Buskard ANL, Strand KL, Roberson KB, Michiels ER, Kuhn JE, Lopez FA, Signorile JF Abstract BACKGROUND: Declines in strength and power are cardinal symptoms of Parkinson's disease (PD), a progressive neuromuscular disorder. Progressive…