Mitochondrial DNA variation in Parkinson’s disease: Analysis of “out-of-place” population variants as a risk factor

Mitochondrial DNA variation in Parkinson’s disease: Analysis of “out-of-place” population variants as a risk factor
Front Aging Neurosci. 2022 Jul 14;14:921412. doi: 10.3389/fnagi.2022.921412. eCollection 2022.ABSTRACTMitochondrial DNA (mtDNA), a potential source of mitochondrial dysfunction, has been implicated in Parkinson's disease (PD). However, many previous studies investigating associations between mtDNA population variation and PD reported inconsistent or contradictory findings. Here, we investigated an alternative hypothesis to determine whether mtDNA variation could play a significant role in PD ... read more
Source: PubMedPublished on 2022-08-01By Amica C Müller-Nedebock