NASA laboratory ‘humanely euthanized’ 27 of its research monkeys in one day due to ‘advancing age’

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• One small step for man, one giant leap for Parkinson’s August 8, 2019 A groundbreaking International Space Station experiment – which has seen human brain cells launched into space – is well underway as researchers look to the stars to discover what triggers Parkinson’s In a first-of-its-kind study, US space agency NASA has collaborated with Parkinson’s researchers to send brain cells into space to learn more about the condition. As part of the…
• 2019: Year in review December 31, 2019   In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2019. Month-by-month we will briefly discuss some of the major pieces of research/announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies to any researchers who…
• 2020: Year in Review January 1, 2021 # # # # In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2020. Month-by-month we will briefly discuss some of the major pieces of research/ announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies…
• Psychosis Treatments October 28, 2019 Psychosis Treatments PSYCHOSIS TREATMENTS Generic Brand Form Indication Adult Initial Dose Adult Dose Titration First-Generation Antipsychotics chlorpromazine HCl — tabs Psychosis. Mania Less acutely disturbed: 25mg three times dailyOutpatient: 10mg 3–4 times daily or 25mg 2–3 times dailySevere cases: 25mg three times daily Inpatient: 500–1000mg/dayLess acutely disturbed: 400mg/dayOutpatient: 200–800mg/day Increase dose gradually until symptoms are controlled. Continue optimum dosage for…
• Parkinson’s Experiment to Be Aboard Next Flight to International Space Station August 9, 2017 The United States is just four days away from sending a SpaceX rocket to the International Space Station whose cargo will include a Parkinson’s disease experiment. National Aeronautics and Space Administration officials said the experiment will involve growing leucine-rich repeat kinase 2 protein crystals in the near-zero-gravity conditions of space. Scientists hope the LRRK2 crystals will be larger and more regular in space, allowing them to…
• Let’s Talk About Palliative Care and Parkinson’s disease January 12, 2021 People with Parkinson’s disease (PD) and their care partners are always searching for ways to make their lives easier, healthier and fuller. Using the principles of palliative care to enhance PD-specific care is one way to do that. Palliative care is a medical approach for those with complex illnesses, in which the focus is on maximizing quality of life. This…
• Parkinson’s Disease Research: A Commentary from the Stands and the Playing Field May 11, 2017 “You can have a very bad end with Parkinson’s, but on the other hand, you can be like me, because I’m lucky. I’m not having a bad end.” Margo MacDonald “My age makes me think how valuable life is. How bad is something like Parkinson’s in relation to not having life at all?” Michael J. Fox Introduction: Last month, together…
• July 14, 2019 - Parkinson's Weekly Update July 13, 2019 This Week's Highlights: NASA sending Parkinson’s brain cells to space; Is red light therapy a potential hope for treating pain associated with PD; Understanding exercise intensity; reconnecting through rhythm; Info on Parkinson’s meds & nutritional supplements; gene therapy nears trial for PD-GBA; Young Onset Parkinson’s Disease (YOPD); How long do the effects of Deep Brain Stimulation (DBS) surgery last?; MS,…
• Growing LRRK2 Protein Crystals in Space Could Help Scientists Better Understand and Treat Parkinson’s April 5, 2019 Crystals of the LRRK2 protein grown aboard the International Space Station could improve the understanding of Parkinson’s disease and help develop more effective therapies for this disease, according to researchers. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common genetic cause of Parkinson’s and result in excessive activation of the LRKK2 protein. Although treatments designed to block the LRRK2 protein…
• Key Parkinson’s Protein Gets Starring Research Role on International Space Station July 21, 2017 When a resupply mission lifts off in August bound for the International Space Station, it will be carrying an important cargo for researchers studying Parkinson’s disease: a protein considered  to be a key to potential future therapies. The leucine-rich repeat kinase 2 (LRRK2) protein will be the focus of an experiment conducted on the Space Station. It is hoped that the microgravity conditions aboard the…
• Prevail lands on a Lilly pad December 15, 2020 # # # # 2020 has been a dreadful year for most of the world – burdened by the outbreak and consequences of COVID-19. Despite this, there has been a steady stream of biotech acquisitions related to Parkinson’s which have helped to keep morale high in the PD research community. In October alone, we saw the Portuguese pharmaceutical company Bial…
• Dear Parkinson’s Care Partners November 6, 2019 Dear Parkinson’s Care Partner, Being a care partner to someone with Parkinson’s isn’t easy. It takes time, effort, energy and love, and chances are, it’s not what you signed up for. However, if you’re reading this post, no matter how you found yourself in this position, you stand together with hundreds of thousands of people around the world who identify…
• Palliative Care Leads to Better Quality of Life than Standard Care for PDRD Patients, Study Finds February 12, 2020 Palliative care — focusing on physical, psychosocial and spiritual treatment — for people with Parkinson’s disease and related disorders (PDRD) led to a significantly better quality of life (QoL) than standard care alone, a study finds. Easing of both non-motor and motor symptom severity was linked to palliative care intervention — and those with the greatest needs benefited the most,…
• Excellent Choices for Parkinson’s Disease Care September 19, 2018 While searching for a movement disorders doctor, I happened upon a government listing for Parkinson’s Disease (PD) Centers of Excellence, which fascinated me. According to the Parkinson’s Foundation, PD Centers of Excellence deliver care worldwide to more than 127,000 patients. The centers “advance research to improve the lives of everyone with Parkinson’s treated at centers and beyond, and for future generations.” They…
• Care Planning for a Parent Living with Parkinson’s August 1, 2019 We recently sat down with a good friend of the Foundation, Bud Rockhill, to talk about his experience caring for his mom who had Parkinson’s. He had so many great tips and insights into nearly every aspect of her care that we asked if we could share them with our community. Please note that these were Bud’s experiences, and this…
• Giant leap for research as NASA launches Parkinson’s protein into space August 14, 2017 Blasting off today, the SpaceX Falcon 9 rocket cargo contains a protein sample crucial to solving an important piece of the Parkinson’s puzzle – watch the launch live here At 17:31 BST today, NASA will launch the SpaceX Falcon 9 rocket at Cape Canaveral, Florida, US. The rocket’s cargo, bound for the International Space Station, contains an important package for…
• Part 1 of 2017 PWR! (Parkinson Wellness Recovery) Retreat: Pictures With Great Memories July 23, 2017 “Just put one foot in front of the other.”  Austin Peck “Coming together is a beginning; keeping together is progress; working together is success.”  Henry Ford Introduction to Part 1: From May 28-June 3, >100 people came to Scottsdale, Arizona for the PWR! Retreat. The final tally had >50 people-with-Parkinson’s, more than 30 care partners and ~20 physical therapists/fitness professionals,…
• Milestones in Parkinson’s Disease Research and Discovery April 11, 2017 “The real voyage of discovery consists not in seeking new landscapes, but in having new eyes.” Marcel Proust “The process of scientific discovery is, in effect, a continual flight from wonder.” Albert Einstein Preface:  Happy birthday to James Parkinson (neurologist, geologist, scientist, activist),  born April 11, 1755 and died December 21, 1824.  World Parkinson’s Day April 11, 2017. Introduction to…
• Parkinsonism Treatments August 26, 2019 Parkinsonism Treatments PARKINSONISM TREATMENTS Generic Brand Form Strength Adult Dose ANTICHOLINERGICS benztropine — scored tabs 0.5mg, 1mg, 2mg Initially 0.5−1mg at bedtime. May increase by 0.5mg at 5−6 day intervals; max 6mg daily. Cogentin amps 1mg/mL hyoscy–amine sulfate NuLev chew–able melt tabs 0.125mg 1−2 tabs every 4hrs or as needed; max 12 tabs/day trihexy–phenidyl — scored tabs 2mg, 5mg Give in 3−4…
• Comparative study of striatum GABA concentrations and magnetic resonance spectroscopic imaging in Parkinson's disease monkeys. August 10, 2019 Related ArticlesComparative study of striatum GABA concentrations and magnetic resonance spectroscopic imaging in Parkinson's disease monkeys. BMC Neurosci. 2019 Aug 08;20(1):42 Authors: Huang L, Ren Y, Zeng Z, Ren H, Li S, He S, He F, Li X Abstract BACKGROUND: Parkinson's disease is a progressive degenerative nervous system disease. Recent studies have shown that secondary changes in the GABA system…
• The 2019 Linked Clinical Trials meeting October 16, 2019   Things were a bit quiet on the SoPD over the summer, but for good reasons. There was a short hiatus for a family break, but the rest of the time I was rather occupied with the day job. Tremendous efforts were being made at the Cure Parkinson’s Trust, as we were gearing up for our main event of the…