Neuronal and glial characterization in the rostrocaudal axis of the human anterior olfactory nucleus: Involvement in Parkinson’s disease

Neuronal and glial characterization in the rostrocaudal axis of the human anterior olfactory nucleus: Involvement in Parkinson’s disease
Front Neuroanat. 2022 Jul 18;16:907373. doi: 10.3389/fnana.2022.907373. eCollection 2022.ABSTRACTHyposmia is one of the prodromal symptoms of Parkinson's disease (PD) and a red flag in clinical diagnosis. Neuropathologically, this sign correlates with α-synuclein involvement in the anterior olfactory nucleus (AON). Neurodegeneration, microgliosis, and astrogliosis in AON are poorly studied, and bulbar AON is the focus of these studies with contradictory results. ... read more
Source: PubMedPublished on 2022-08-04By Sandra Villar-Conde