Neuroprotective effects of TRPV1 by targeting GDF11 in the Mpp+/MPTP-induced Parkinson’s disease model

Neuroprotective effects of TRPV1 by targeting GDF11 in the Mpp+/MPTP-induced Parkinson’s disease model
Biochem Biophys Res Commun. 2022 Jul 19;623:104-110. doi: 10.1016/j.bbrc.2022.07.058. Online ahead of print.ABSTRACTProtecting dopaminergic neurons is a key approach in the prevention of Parkinson's disease (PD). Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel that is widely distributed in the mammalian nervous system. In this study, we designed experiments to investigate the effect and mechanisms of TRPV1 ... read more
Source: PubMedPublished on 2022-08-03By Kaiyong Zhang