Novel druggable mechanism of Parkinson’s disease: Potential therapeutics and underlying pathogenesis based on ferroptosis

Novel druggable mechanism of Parkinson’s disease: Potential therapeutics and underlying pathogenesis based on ferroptosis
Med Res Rev. 2023 Mar 16. doi: 10.1002/med.21939. Online ahead of print.ABSTRACTGenetics, age, environmental factors, and oxidative stress have all been implicated in the development of Parkinson's disease (PD); however, a complete understanding of its pathology remains elusive. At present, there is no cure for PD, and currently available therapeutics are insufficient to meet patient needs. Ferroptosis, a distinctive iron-dependent ... read more
Source: PubMedPublished on 2023-03-16By Xiaoying Jiang