Obstructive sleep apnea and the risk of Alzheimer’s disease and Parkinson disease: A Mendelian randomization study OSA, Alzheimer’s disease and Parkinson disease

Obstructive sleep apnea and the risk of Alzheimer’s disease and Parkinson disease: A Mendelian randomization study OSA, Alzheimer’s disease and Parkinson disease
Sleep Med. 2022 Jun 9;97:55-63. doi: 10.1016/j.sleep.2022.06.004. Online ahead of print.ABSTRACTBACKGROUND: Previous studies reported that obstructive sleep apnea (OSA) was associated with neurodegenerative diseases. However, whether these associations are causal are still unsettled. In our study, we investigated the causal effects of genetically-predicted OSA on Alzheimer's disease (AD) and Parkinson disease (PD).METHODS: We implemented two-sample Mendelian randomization to judge causation ... read more
Source: PubMedPublished on 2022-06-20By Jinwei Li