Pipeline Moves: Advancement prospects plunge for Parkinson’s … – Clinical Trials Arena

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• The road ahead: 2022 January 20, 2022 # # # # The first post at the start of each year on the SoPD website tries to provide an overview of where things are in the search for ‘disease modifying’ therapies for Parkinson’s.  It is an exercise in managing expectations as well as discussing what research events are scheduled for the next year so that we can keep…
• The road ahead: 2021 January 25, 2021 # # # # At the start of each year, it is a useful practise to layout what is planned over the next 12 months. The events that are scheduled for the year to come, so that we can keep an eye out for them. Obviously, where 2021 will end actually is unpredictable, but an outline of what is scheduled…
• The drug development pipeline for Parkinson’s December 2, 2020 # # # # For a long time a regular request from SoPD readers has been to provide an overview of the clinical trial landscape for Parkinson’s, particularly in the area of drug development. Such projects are difficult, however, as the landscape is broad and dynamic – lots of different approaches being applied and new entrants continually entering the arena.…
• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• EJS-ACT PD June 26, 2021 # # # # This week an announcement was made regarding The Edmond J. Safra Accelerating Clinical Treatments for Parkinson’s Disease (EJS-ACT PD) Initiative. It is hoping to revolutionise the way clinical trials for potentially disease-modifying drugs for Parkinson’s are conducted. The project is focused on the setting up a multi-arm, multi-stage (MAMS) platform for evaluating new therapies for PD.…
• Promising treatments in the 2023 Parkinson’s clinical trials pipeline August 4, 2023 Note: The update provided below is for informational purposes only. Any treatments described are still in experimental stages and have not been approved by Health Canada. Please speak with your doctor for any questions regarding your treatment plan.  New therapies progress through the clinical trials testing pipeline each year with the goal of improving the quality of life for people…
• The promising treatments in the 2022 Parkinson’s clinical trials pipeline June 28, 2022 As we know the Parkinson’s research community is hard at work to find therapies and treatments to improve the quality of life of Canadians living with Parkinson’s and ultimately find a cure. An article outlining the current clinical trials pipeline for Parkinson’s was recently published in the Journal of Parkinson’s Disease. Here are some of the key highlights. For a…
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• 2020: Year in Review January 1, 2021 # # # # In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2020. Month-by-month we will briefly discuss some of the major pieces of research/ announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies…
• Pipeline Moves: advancement prospects jump for Parkinson's ... - Clinical Trials Arena March 21, 2023 Pipeline Moves: advancement prospects jump for Parkinson's ...  Clinical Trials Arena
• Pipeline Moves: Advancement prospects fall for GM1 gene therapy ... - Clinical Trials Arena June 27, 2023 Pipeline Moves: Advancement prospects fall for GM1 gene therapy ...  Clinical Trials Arena
• Monthly Research Review: January 2022 January 31, 2022 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during January 2022. The post is divided into 10 parts based on the type of research: Top 6 pieces of Parkinson’s news Articles of general interest Basic biology…
• Denali’s Phase I results May 27, 2021 # # # # Leucine-rich repeat kinase 2 (or LRRK2) is a large, multi function protein that is associated with Parkinson’s. People with genetic variations in the region of DNA that provides the instructions for making LRRK2 protein have a higher risk of developing the condition. In many cases of Parkinson’s, LRRK2 can become hyperactive. Researchers and biotech companies have…
• Pipeline Moves: CuraSen Phase I termination slashes likelihood of further study in Parkinson's - Clinical Trials Arena February 8, 2022 Pipeline Moves: CuraSen Phase I termination slashes likelihood of further study in Parkinson's  Clinical Trials Arena
• Monthly Research Review – February 2021 February 28, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during February 2021. The post is divided into eight parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news…
• Polar Plunge November 12, 2020 Take the plunge and brave ice-cold waters for a cure!  It’s time to dig out your swimsuit and take a dip to help raise awareness and funds The Cure Parkinson’s Trust (CPT) this Christmas. Whether you take part in the sea, an open water facility, or in your polar paddling pool at home, you can complete this challenge whenever you…
• Benefits of cold water: Health guru and extreme athlete Wim Hof says we have ‘power within’ to heal disease March 30, 2023 The ability to control our health could be right inside us. This is according to the philosophy and practices of Dutch athlete Wim Hof, father of the Wim Hof Method. Hof, 63, revealed how his teachings have revolutionized public health in an on-camera interview from the Netherlands with Fox News Digital. LIFE-CHANGING COLD THERAPY HELPS PENNSYLVANIA MOM WITH AWFUL BACK…
• Pipeline Moves: AbbVie and Janssen terminate Phase III lymphoma ... - Clinical Trials Arena December 20, 2022 Pipeline Moves: AbbVie and Janssen terminate Phase III lymphoma ...  Clinical Trials Arena
• Ask the expert: How can clinical trials “slow, stop and reverse” Parkinson’s? September 24, 2020 What are clinical trials, why are they so important ­– and what does taking part involve? We talk to Dr Simon Stott and Helen Matthews from The Cure Parkinson’s Trust about how clinical trials help researchers better understand Parkinson’s disease and what potential participants need to know Why are clinical trials important in Parkinson’s disease research? Helen Matthews, deputy CEO…
• The Outlook Is Encouraging: Researchers Evaluate a Pipeline of Clinical Trials Targeting Parkinson’s Disease August 3, 2020 PD is a neurodegenerative condition for which there is currently no cure. The incidence of PD is increasing, with the number of cases expected to double worldwide by 2040. The majority of current pharmacological treatments for PD were approved for clinical use in the second half of the last century, and they only provide symptomatic relief. Derivatives of these therapies…
• The Outlook Is Encouraging: Researchers Evaluate a Pipeline of Clinical Trials Targeting Parkinson’s Disease August 3, 2020 PD is a neurodegenerative condition for which there is currently no cure. The incidence of PD is increasing, with the number of cases expected to double worldwide by 2040. The majority of current pharmacological treatments for PD were approved for clinical use in the second half of the last century, and they only provide symptomatic relief. Derivatives of these therapies…
• Monthly Research Review – July 2021 July 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during July 2021. The post is divided into 10 parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…