Platelets’ Nanomechanics and Morphology in Neurodegenerative Pathologies

Platelets’ Nanomechanics and Morphology in Neurodegenerative Pathologies
Biomedicines. 2022 Sep 9;10(9):2239. doi: 10.3390/biomedicines10092239.ABSTRACTThe imaging and force-distance curve modes of atomic force microscopy (AFM) are explored to compare the morphological and mechanical signatures of platelets from patients diagnosed with classical neurodegenerative diseases (NDDs) and healthy individuals. Our data demonstrate the potential of AFM to distinguish between the three NDDs-Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Alzheimer's disease ... read more
Source: PubMedPublished on 2022-09-23By Velichka Strijkova