pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway

pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway
Int Immunopharmacol. 2023 Jan 21;116:109727. doi: 10.1016/j.intimp.2023.109727. Online ahead of print.ABSTRACTNeuroinflammation is closely related to the etiology and progression of neurodegenerative diseases such as Parkinson disease and Alzheimer disease. pNaktide, an Src inhibitor, exerts antioxidant effects by mimicking Na/K-ATPase. It has been verified that its anti-inflammation and anti-oxidation ability could be embodied in obesity, steatohepatitis, uremic cardiomyopathy, aging, and prostate ... read more
Source: PubMedPublished on 2023-01-23By Qinglan Zong