Presence but not the timing of onset of REM sleep behavior disorder distinguishes evolution patterns in Parkinson’s disease

Presence but not the timing of onset of REM sleep behavior disorder distinguishes evolution patterns in Parkinson’s disease
Neurobiol Dis. 2023 Mar 15:106084. doi: 10.1016/j.nbd.2023.106084. Online ahead of print.ABSTRACTBACKGROUND: Rapid eye movement (REM) sleep behavior disorder (RBD) could develop preceding or come after motor symptoms during Parkinson's disease (PD). It remains unknown that whether PD with different timing of RBD onset relative to motor symptoms suggests different spatiotemporal sequences of neurodegeneration. This study aimed to explore the sequence ... read more
Source: PubMedPublished on 2023-03-17By Sijia Tan