Profiling the Biochemical Signature of GBA-Related Parkinson’s Disease in Peripheral Blood Mononuclear Cells

Profiling the Biochemical Signature of GBA-Related Parkinson’s Disease in Peripheral Blood Mononuclear Cells
Mov Disord. 2021 Feb 22. doi: 10.1002/mds.28496. Online ahead of print.ABSTRACTBACKGROUND: GBA mutations are the commonest genetic risk factor for Parkinson's disease (PD) and also impact disease progression.OBJECTIVE: The objective of this study was to define a biochemical profile that could distinguish GBA-PD from non-mutated PD.METHODS: 29 GBA-PD, 37 non-mutated PD, and 40 controls were recruited; α-synuclein levels in plasma, ... read more
Source: PubMedPublished on 2021-02-22By Micol Avenali