Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease

Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease
Cell Rep Med. 2022 Jun 21;3(6):100661. doi: 10.1016/j.xcrm.2022.100661.ABSTRACTParkinson's disease (PD) is a growing burden worldwide, and there is no reliable biomarker used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients with neurological symptoms and should closely reflect alterations in PD patients' brains. Here, we describe a scalable and sensitive mass spectrometry (MS)-based proteomics workflow for ... read more
Source: PubMedPublished on 2022-06-22By Ozge Karayel