Putaminal y-Aminobutyric Acid Modulates Motor Response to Dopaminergic Therapy in Parkinson’s Disease

Putaminal y-Aminobutyric Acid Modulates Motor Response to Dopaminergic Therapy in Parkinson’s Disease
Mov Disord. 2021 Jun 7. doi: 10.1002/mds.28674. Online ahead of print.ABSTRACTBACKGROUND: Motor response to dopaminergic therapy is a characteristic of patients with Parkinson's disease (PD). Whether nondopaminergic neurotransmitters contribute to treatment response is uncertain.OBJECTIVES: The aim of this study is to determine whether putaminal y-aminobutyric acid (GABA) levels are associated with dopaminergic motor response.METHODS: We assessed putaminal GABA levels in ... read more
Source: PubMedPublished on 2021-06-07By Aline D Seger