Rapid and Reversible Development of Axonal Varicosities: A New Form of Neural Plasticity

Rapid and Reversible Development of Axonal Varicosities: A New Form of Neural Plasticity
Front Mol Neurosci. 2021 Feb 3;14:610857. doi: 10.3389/fnmol.2021.610857. eCollection 2021.ABSTRACTAxonal varicosities are enlarged, heterogeneous structures along axonal shafts, profoundly affecting axonal conduction and synaptic transmission. They represent a key pathological feature believed to develop via slow accumulation of axonal damage that occurs during irreversible degeneration, for example in mild traumatic brain injury (mTBI), Alzheimer's and Parkinson's diseases, and multiple sclerosis. ... read more
Source: PubMedPublished on 2021-02-22By Chen Gu