Reduced coupling of global brain function and cerebrospinal fluid dynamics in Parkinson’s disease

Reduced coupling of global brain function and cerebrospinal fluid dynamics in Parkinson’s disease
J Cereb Blood Flow Metab. 2023 Mar 16:271678X231164337. doi: 10.1177/0271678X231164337. Online ahead of print.ABSTRACTDysfunction of the glymphatic system, an intracranial clearance pathway that drains misfolded proteins, has been implicated in the onset of Parkinson's disease (PD). Recently, the coupling strength of global blood-oxygen-level-dependent (gBOLD) signals and cerebrospinal fluid (CSF) inflow dynamics have been suggested to be an indicator of glymphatic ... read more
Source: PubMedPublished on 2023-03-17By Zhiyun Wang