Regulation of the tubulin polymerization-promoting protein by Ca2+/S100 proteins

Regulation of the tubulin polymerization-promoting protein by Ca2+/S100 proteins
Cell Calcium. 2021 Mar 27;96:102404. doi: 10.1016/j.ceca.2021.102404. Online ahead of print.ABSTRACTTo elucidate S100 protein-mediated signaling pathways, we attempted to identify novel binding partners for S100A2 by screening protein arrays carrying 19,676 recombinant glutathione S-transferase (GST)-fused human proteins with biotinylated S100A2. Among newly discovered putative S100A2 interactants, including TMLHE, TRH, RPL36, MRPS34, CDR2L, OIP5, and MED29, we identified and characterized the ... read more
Source: PubMedPublished on 2021-04-08By Seita Doi