Restoration of Noradrenergic Function in Parkinson’s Disease Model Mice

Restoration of Noradrenergic Function in Parkinson’s Disease Model Mice
ASN Neuro. 2021 Jan-Dec;13:17590914211009730. doi: 10.1177/17590914211009730.ABSTRACTDysfunction of the central noradrenergic and dopaminergic systems is the primary neurobiological characteristic of Parkinson's disease (PD). Importantly, neuronal loss in the locus coeruleus (LC) that occurs in early stages of PD may accelerate progressive loss of dopaminergic neurons. Therefore, restoring the activity and function of the deficient noradrenergic system may be an important therapeutic ... read more
Source: PubMedPublished on 2021-05-04By Kui Cui