Sertraline treatment influences [18F]FE-PE2I PET imaging for Parkinsonism

Sertraline treatment influences [18F]FE-PE2I PET imaging for Parkinsonism
EJNMMI Res. 2023 May 23;13(1):46. doi: 10.1186/s13550-023-01000-6.ABSTRACTBACKGROUND: The dopamine transporter (DaT) PET ligand [18F]FE-PE2I is used to aid the diagnosis of Parkinson's disease. After encountering four patients with a history of daily sertraline use, who all showed atypical findings on [18F]FE-PE2I PET, we suspected that the selective serotonin reuptake inhibitor (SSRI), sertraline, might interfere with the results and lead to ... read more
Source: PubMedPublished on 2023-05-23By Thomas E H Justesen