Specific Form of Alpha-Synuclein Linked to More Severe Parkinson’s Symptoms in Early Study

Specific Form of Alpha-Synuclein Linked to More Severe Parkinson’s Symptoms in Early Study
Small amounts of a particular form of alpha-synuclein, known as beta-sheet, may cause a significant loss of dopamine-releasing neurons by recruiting more alpha-synuclein molecules, leading to Parkinson’s-like symptoms and disease progression, according to a recent lab study. The study, “Defining α-synuclein species responsible for Parkinson disease phenotypes in mice,” was published in the Journal of Biological Chemistry. In Parkinson’s, a ... read more
Source: Parkinson’s News TodayPublished on 2019-07-11By Catarina Silva