Structural genomics of the human dopamine receptor system

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
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• Monthly research review – March 2021 March 31, 2021 # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during March 2021. The post is divided into ten parts based on the type of research: Top 5 pieces of Parkinson’s news Articles of general interest Basic biology…
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• Structural genomics of the human dopamine receptor system May 23, 2023 Cell Res. 2023 May 23. doi: 10.1038/s41422-023-00808-0. Online ahead of print.ABSTRACTThe dopaminergic system, including five dopamine receptors (D1R to D5R), plays essential roles in the central nervous system (CNS); and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders, including Parkinson's Disease (PD) and schizophrenia. Here, we report cryo-EM structures of all five subtypes of human…
• Structural genomics of the human dopamine receptor system May 23, 2023 Cell Res. 2023 May 23. doi: 10.1038/s41422-023-00808-0. Online ahead of print.ABSTRACTThe dopaminergic system, including five dopamine receptors (D1R to D5R), plays essential roles in the central nervous system (CNS); and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders, including Parkinson's Disease (PD) and schizophrenia. Here, we report cryo-EM structures of all five subtypes of human…
• Structural genomics of the human dopamine receptor system May 23, 2023 Cell Res. 2023 May 23. doi: 10.1038/s41422-023-00808-0. Online ahead of print.ABSTRACTThe dopaminergic system, including five dopamine receptors (D1R to D5R), plays essential roles in the central nervous system (CNS); and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders, including Parkinson's Disease (PD) and schizophrenia. Here, we report cryo-EM structures of all five subtypes of human…
• Structural genomics of the human dopamine receptor system May 23, 2023 Cell Res. 2023 May 23. doi: 10.1038/s41422-023-00808-0. Online ahead of print.ABSTRACTThe dopaminergic system, including five dopamine receptors (D1R to D5R), plays essential roles in the central nervous system (CNS); and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders, including Parkinson's Disease (PD) and schizophrenia. Here, we report cryo-EM structures of all five subtypes of human…
• Structural genomics of the human dopamine receptor system May 23, 2023 Cell Res. 2023 May 23. doi: 10.1038/s41422-023-00808-0. Online ahead of print.ABSTRACTThe dopaminergic system, including five dopamine receptors (D1R to D5R), plays essential roles in the central nervous system (CNS); and ligands that activate dopamine receptors have been used to treat many neuropsychiatric disorders, including Parkinson's Disease (PD) and schizophrenia. Here, we report cryo-EM structures of all five subtypes of human…
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