Suppression of neuroinflammation and α-synuclein oligomerization by rotarod walking exercise in subacute MPTP model of Parkinson’s disease

Suppression of neuroinflammation and α-synuclein oligomerization by rotarod walking exercise in subacute MPTP model of Parkinson’s disease
Neurochem Int. 2023 Mar 15:105519. doi: 10.1016/j.neuint.2023.105519. Online ahead of print.ABSTRACTParkinson's disease (PD) belongs to an α-synucleinopathy and manifests motor dysfunction attributed to nigrostriatal dopaminergic degeneration. In clinical practice, the beneficial role of physical therapy such as motor skill learning training has been recognized in PD-linked motor defects. Nevertheless, the disease-modifying effects of motor skill learning training on PD-related pathology ... read more
Source: PubMedPublished on 2023-03-17By Yea-Hyun Leem