Systemic metabolic alteration dependent on the thyroid-liver axis in early PD

Systemic metabolic alteration dependent on the thyroid-liver axis in early PD
Ann Neurol. 2022 Sep 21. doi: 10.1002/ana.26510. Online ahead of print.ABSTRACTOBJECTIVE: Parkinson's disease (PD) is a common neurodegenerative disease characterized by initial involvement of the olfactory bulb/amygdala or autonomic nerves followed by nigral degeneration. Although autonomic innervation strictly regulates multiorgan systems including endocrine functions, circulation, and digestion, how dysautonomia in PD affects systemic metabolism has not been identified. In this ... read more
Source: PubMedPublished on 2022-09-21By Kengo Miyamoto