The ‘α-synucleinopathy syndicate’: multiple system atrophy and Parkinson’s disease

The ‘α-synucleinopathy syndicate’: multiple system atrophy and Parkinson’s disease
J Neural Transm (Vienna). 2023 May 25. doi: 10.1007/s00702-023-02653-2. Online ahead of print.ABSTRACTMultiple System Atrophy (MSA) and Parkinson's diseases (PD) are elite members of the α-synucleinopathy organization. Aberrant accumulations of the protein α-synuclein characterize them. A plethora of evidence indicates the involvement of these rogue inclusions in a cascade of events that disturb cellular homeostasis resulting in neuronal dysfunction. These ... read more
Source: PubMedPublished on 2023-05-25By Jeswinder Sian-Hulsmann