The effects of safinamide on dysphagia in Parkinson’s disease

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
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• The effects of safinamide on dysphagia in Parkinson's disease May 25, 2023 PLoS One. 2023 May 25;18(5):e0286066. doi: 10.1371/journal.pone.0286066. eCollection 2023.ABSTRACTDysphagia is a potentially fatal symptom of Parkinson's disease (PD) and is characterized by frequent silent aspiration, a risk factor for aspiration pneumonia. The transdermal dopamine agonist rotigotine alleviates dysphagia in patients with PD and is more effective than oral levodopa, suggesting the importance of continuous dopaminergic stimulation (CDS) in swallowing. Safinamide…
• The effects of safinamide on dysphagia in Parkinson's disease May 25, 2023 PLoS One. 2023 May 25;18(5):e0286066. doi: 10.1371/journal.pone.0286066. eCollection 2023.ABSTRACTDysphagia is a potentially fatal symptom of Parkinson's disease (PD) and is characterized by frequent silent aspiration, a risk factor for aspiration pneumonia. The transdermal dopamine agonist rotigotine alleviates dysphagia in patients with PD and is more effective than oral levodopa, suggesting the importance of continuous dopaminergic stimulation (CDS) in swallowing. Safinamide…
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