The emerging landscape of single-molecule protein sequencing technologies

The emerging landscape of single-molecule protein sequencing technologies
Nat Methods. 2021 Jun;18(6):604-617. doi: 10.1038/s41592-021-01143-1. Epub 2021 Jun 7.ABSTRACTSingle-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is not yet established. Here we describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually ... read more
Source: PubMedPublished on 2021-06-08By Javier Antonio Alfaro