Therapeutic Drugs and the Blood Brain Barrier – The National Law Review

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
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• Orthostatic Hypotension and Parkinson's Disease October 27, 2016 One of my fellow boxers at the Rock Steady Boxing affiliate in Hilton Head/Bluffton, SC has been having issues of dizziness and brain fog/light headedness. He's not alone, as 1 in 5 people with Parkinson's are also diagnosed with Orthostatic Hypotension. I've been collecting some information to help him prepare for his next doctor's appointment, and thought this may be…
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• Monthly Research Review – November 2019 November 30, 2019   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during November 2019. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• Monthly Research Review – December 2020 December 31, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• Monthly research review – October 2019 October 31, 2019   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during October 2019. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Other news Review…
• June 2, 2019 - Parkinson's Weekly Update June 1, 2019 Weekly Update - Highlights include: World Parkinson Congress 2019 heads to Kyoto, Japan for the epic battle of "Parkinson's Disease vs. Chopsticks - Will We Go Home Hungry?"; focused ultrasound and PD; NIH awards $3 million grant for 5-year PD exercise study; deteriorating financial skills, dementia and brain plaques; hockey pucks for Parkinson's; inspiring people with PD; how DBS changes…
• Importance of Magnesium in the Brain and Magnesium Threonate is Neuroprotective in a Mouse Model of Parkinson’s March 5, 2020 “The world may be broken, but hope is not crazy.” John Green “Our eternal message of hope is that dawn will come.” Martin Luther King, Jr. Introduction:  Epidemiological studies show that magnesium deficiency is associated with a Parkinson’s like syndrome called Parkinson-Dementia Syndrome (PDC). PDC patients have progressive cognitive decline, parkinsonian, and the loss of the dopaminergic neurons in the substantia…
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• 2019: Year in review December 31, 2019   In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2019. Month-by-month we will briefly discuss some of the major pieces of research/announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies to any researchers who…
• B Vitamins (Folate, B6, B12) Reduce Homocysteine Levels Produced by Carbidopa/Levodopa Therapy September 12, 2017 “The excitement of vitamins, nutrition and metabolism permeated the environment.” Paul D. Boyer “A substance that makes you ill if you don’t eat it.” Albert Szent-Gyorgy Introduction: Claire McLean, an amazing-PT who is vital to my life managing my Parkinson’s, posted a very interesting article about the generation of homocysteine from the metabolism of levodopa to dopamine in the brain.…