Tubulin deacetylase NDST3 modulates lysosomal acidification: Implications in neurological diseases

Tubulin deacetylase NDST3 modulates lysosomal acidification: Implications in neurological diseases
Bioessays. 2022 Sep 22:e2200110. doi: 10.1002/bies.202200110. Online ahead of print.ABSTRACTNeurological diseases (NDs), featured by progressive dysfunctions of the nervous system, have become a growing burden for the aging populations. N-Deacetylase and N-sulfotransferase 3 (NDST3) is known to catalyze deacetylation and N-sulfation on disaccharide substrates. Recently, NDST3 is identified as a novel deacetylase for tubulin, and its newly recognized role in ... read more
Source: PubMedPublished on 2022-09-22By Qing Tang