Unravelling the Structural Organization of Individual α-Synuclein Oligomers Grown in the Presence of Phospholipids

Unravelling the Structural Organization of Individual α-Synuclein Oligomers Grown in the Presence of Phospholipids
J Phys Chem Lett. 2021 May 4:4407-4414. doi: 10.1021/acs.jpclett.1c00820. Online ahead of print.ABSTRACTParkinson's disease (PD) is a severe neurological disorder that affects more than 1 million people in the U.S. alone. A hallmark of PD is the formation of intracellular α-synuclein (α-Syn) protein aggregates called Lewy bodies (LBs). Although this protein does not have a particular localization in the central ... read more
Source: PubMedPublished on 2021-05-04By Tianyi Dou