Upregulated DNA Damage-Linked Biomarkers in Parkinson’s Disease Model Mice

Upregulated DNA Damage-Linked Biomarkers in Parkinson’s Disease Model Mice
ASN Neuro. 2023 Jan-Dec;15:17590914231152099. doi: 10.1177/17590914231152099.ABSTRACTThe present study examined expression of DNA damage markers in VMAT2 Lo PD model mice. The results demonstrate there is a significant increase in these DNA damage markers mostly in the brain regions of 18- and 23-month-old model mice, indicating oxidative stress-induced DNA lesion is an important pathologic feature of this mouse model.PMID:36683340 | DOI:10.1177/17590914231152099 ... read more
Source: PubMedPublished on 2023-01-23By Fei Zeng