Volunteers share Sanofi Pasteur/GSK COVID-19 vaccine trial experiences – KSRO

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• The road ahead: 2020 January 5, 2020 Here at the SoPD, we are primarily interested in disease modification for Parkinson’s. While there is a great deal of interesting research exploring the causes of the condition, novel symptomatic therapies, and other aspects of Parkinson’s, my focus is generally on the science seeking to slow, stop or reverse the condition. At the start of each year, it is a…
• Monthly Research Review – November 2020 November 30, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during November 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• Update on COVID-19 and Parkinson’s disease October 27, 2020 Latest Research on COVID-19 & Parkinson’s disease UPDATE: This post (originally published in June) has been updated with the latest information available. We will continue to keep this post up-to-date as new information develops. As citizens of the world, we all continue to grapple with the COVID-19 pandemic. And as members of the Parkinson’s disease (PD) community, we continue to have…
• Update on COVID-19 and Parkinson’s disease October 27, 2020 Latest Research on COVID-19 & Parkinson’s disease UPDATE: This post (originally published in June) has been updated with the latest information available. We will continue to keep this post up-to-date as new information develops. As citizens of the world, we all continue to grapple with the COVID-19 pandemic. And as members of the Parkinson’s disease (PD) community, we continue to have…
• Life with Parkinson’s in the Time of COVID-19: April is Parkinson’s Awareness Month April 1, 2020 “The measure of who we are is what we do with what we have.” Vince Lombardi “When you have exhausted all possibilities, remember this: you haven’t.” Thomas Edison Précis: A different world exists today than it did just a few weeks ago, all driven by the COVID-19 pandemic. The virus seemingly favors the elderly who have a pre-existing disease(s); however,…
• Life with Parkinson’s in the Time of COVID-19: April is Parkinson’s Awareness Month April 1, 2020 “The measure of who we are is what we do with what we have.” Vince Lombardi “When you have exhausted all possibilities, remember this: you haven’t.” Thomas Edison Précis: A different world exists today than it did just a few weeks ago, all driven by the COVID-19 pandemic. The virus seemingly favors the elderly who have a pre-existing disease(s); however,…
• Answering Your Questions about Parkinson’s disease and Coronavirus Disease 2019 (COVID-19) December 21, 2020 Answering Your Questions about Parkinson’s disease and Coronavirus Disease 2019 (COVID-19) – Updated People with Parkinson’s disease (PD) have been asking a lot of questions about COVID-19 since the pandemic began and APDA has been here with the answers you need. As such, we have updated our blog post again with additional questions that have come in, along with some new information…
• CMT-3: A better option than doxy? November 22, 2020 # # # # It has been reported by multiple independent research groups that tetracycline-based antibiotic drugs (such as doxycycline) have exhibited neuroprotective properties in models of Parkinson’s. Translation of these preclinical findings into the clinic has, however, been difficult. In addition, concerns have been expressed that long-term use of such agents could bring forward the emergence of antibiotic resistance…
• Volunteers share Sanofi Pasteur/GSK COVID-19 vaccine trial experiences - ABC News December 30, 2020 Volunteers share Sanofi Pasteur/GSK COVID-19 vaccine trial experiences  ABC News
• Making a strong case for GCase November 25, 2019   Novel therapies are increasing being developed to focus on specific subtypes of Parkinson’s. The hope is that if they work on one type of Parkinson’s, then maybe they will also work on others. Many of these new experimental treatments are focused on specific genetic subtypes of the condition, which involve having a specific genetic variation that increases one’s risk…
• Monthly Research Review – December 2020 December 31, 2020   At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2020. The post is divided into seven parts based on the type of research: Basic biology Disease mechanism Clinical research New clinical trials Clinical trial news Conferences/lectures Other news…
• 2020: Year in Review January 1, 2021 # # # # In this end-of-year post, we review the Parkinson’s research that caught our attention at SoPD HQ in 2020. Month-by-month we will briefly discuss some of the major pieces of research/ announcements that have defined the year and advanced our understanding of Parkinson’s. The list is based on nothing more than the author’s personal opinion – apologies…
• Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. December 12, 2020 Related ArticlesSafety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet. 2020 Dec 08;: Authors: Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL, Barnabas SL, Bhorat QE, Bibi S, Briner C, Cicconi P, Collins AM,…
• Is a vaccine for Parkinson’s disease possible? November 3, 2020 As the world awaits an effective vaccine for SARS-CoV2 (the virus that causes COVID-19), vaccines and vaccination are at the front and center of the news and in our minds. A vaccine is a substance that is introduced into the body in order to stimulate the immune system to provide protection against a particular disease. Did you know that many…
• Is a vaccine for Parkinson’s disease possible? November 3, 2020 As the world awaits an effective vaccine for SARS-CoV2 (the virus that causes COVID-19), vaccines and vaccination are at the front and center of the news and in our minds. A vaccine is a substance that is introduced into the body in order to stimulate the immune system to provide protection against a particular disease. Did you know that many…
• Technology Has Broken Healthcare Barriers During the COVID-19 Pandemic December 29, 2020 COVID-19 has prompted clinicians to change how they deliver care and to reallocate resources toward the most urgent needs on a global scale.1 Patients with diseases ranging from Parkinson disease to chronic pain have been forced to wait for extended periods of time for necessary interventions and treatments. Consequently, many have experienced higher levels of pain, depression, and an overall…
• Journey With Parkinson’s: (Part 2) A Different Side of Life November 2, 2020 “Yesterday is but today’s memory, and tomorrow is today’s dream.” Khalil Gibran “Time is free, but it’s priceless. You can’t own it, but you can use it. You can’t keep it, but you can spend it. Once you’ve lost it you can never get it back.” Harvey Mackay Introduction: I am a scientist, trained as a protein chemist with expertise…
• Journey With Parkinson’s: (Part 2) A Different Side of Life November 2, 2020 “Yesterday is but today’s memory, and tomorrow is today’s dream.” Khalil Gibran “Time is free, but it’s priceless. You can’t own it, but you can use it. You can’t keep it, but you can spend it. Once you’ve lost it you can never get it back.” Harvey Mackay Introduction: I am a scientist, trained as a protein chemist with expertise…
• UNS’ Investigational Vaccine UB-312 Holds Potential to Prevent Parkinson’s, Other Neurological Diseases, Data Show November 16, 2018 An investigational vaccine being developed by United Neuroscience (UNS) presented several advantages over traditional vaccines to treat progressive disorders, such as Parkinson’s disease, according to preclinical data. The vaccine, called UB-312, was more selective to prevent toxic aggregates of alpha-synuclein in mouse models of the disease. These latest findings were discussed during the Parkinson’s UK Research Conference 2018 held in York, England. The…
• COVID-19 Exacerbates Some Parkinson’s Symptoms, Study Finds June 2, 2020 COVID-19 infection appears to worsen some symptoms of Parkinson’s disease, requiring adjustments to therapy, according to a recent case study. The study, “Effects of COVID-19 on Parkinson’s disease clinical features: a community-based case-control study,”  was published in the journal Movement Disorders. SARS-CoV-2, the strain of coronavirus responsible for COVID-19 disease, may worsen Parkinson’s disease through several different mechanisms, such as…
• Parkinson’s, Flu Shots & You October 11, 2019 October signals the beginning of influenza season, a time when many wonder, “Should I get a flu shot?”. The short answer is, yes, but for people living with Parkinson’s, there can be additional concerns or questions. Let’s take a look at what you and your care team can do to prepare for the 2019-2020 flu season. Who Should Get a…
• Parkinson’s Vaccine Triggers Solid Immune Response, Phase 1 Clinical Trial Shows June 15, 2017 AFFiRiS’s new Parkinson’s vaccine, AFFITOPE PD03A, triggered a solid immune response against the alpha-Synuclein (aSyn) protein associated with the disease, according to a Phase 1 clinical trial. Patients also tolerated the therapy well, researchers said. Werner Poewe, a professor at Austria’s Medical University Insbruck, presented the results at the 21stInternational Congress of Parkinson’s Disease and Movement Disorders in Vancouver, Canada, June 4-8. He is part of…