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September 15, 2016 at 12:29 am #25170
Fire up your espresso machine.
In this most recent study published in the journal Parkinsonism and Related Disorders, 79 newly diagnosed PD patients received follow up for 4 years.
•Caffeine consumption was associated with a reduced accrual of PD motor disability.
•PD patients with higher caffeine use presented a reduced need for l-Dopa treatment.
•Non-motor symptoms presented a milder progression among PD patients using caffeine.
…considering the whole study period, each additional espresso cup per day (50 mg of caffeine) was more likely associated with 5-point lower UPDRS part III total score, and with 5-point lower NMSQuest total score, but not with UPDRS part IV total score.
UPDRS refers to the Unified Parkinson’s Disease Rating Scale, which is how doctors assess the severity of a patient’s PD. Lower is better. Part III is the clinician-scored and monitored motor evaluation. Part IV, which showed no difference in this study, is about complications of treatment such as dyskinesia and on/off fluctuations. The rating scale is defined at http://www.movementdisorders.org/MDS-Files1/PDFs/Rating-Scales/MDS-UPDRSfinal_Update.pdf
NMSQuest refers to the Nonmotor Symptoms Questionnaire for Parkinson’s Disease, which attempts to provide a comprehensive assessment of the range of nonmotor symptoms in PD. The rating scale is defined at http://www.movementdisorders.org/MDS-Files1/PDFs/MDS-UPDRS-Rating-Scales/NMSQ.pdf
Article in the Daily Express: http://www.express.co.uk/life-style/health/710635/Parkinson-s-disease-symptoms-caffeine-coffee-chocolate-walking
Link to the study abstract (and paid access to full text): http://dx.doi.org/10.1016/j.parkreldis.2016.08.005
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