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- Conjugal parkinsonism is coincidental.
Related ArticlesConjugal parkinsonism is coincidental. Parkinsonism Relat Disord. 2016 12;33:149-150 Authors: Rajput AH, Ferguson LW, Robinson CA, Guella I, Farrer MJ, Rajput A PMID: 27743700 [PubMed - indexed for MEDLINE] ... read more - Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia.Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia. Cell Rep. 2018 Jun 19;23(12):3438-3446.e5 Authors: Ryan MB, Bair-Marshall C, Nelson AB Abstract Action selection relies on the coordinated activity of striatal direct and indirect pathway medium spiny neurons (dMSNs and iMSNs, respectively). Loss of dopamine in Parkinson's disease is thought to ... read more
- Behavioral and neurochemical responses derived from dopaminergic intrastriatal grafts in hemiparkinsonian rats engaged in a novel motor task.Behavioral and neurochemical responses derived from dopaminergic intrastriatal grafts in hemiparkinsonian rats engaged in a novel motor task. J Neurosci Methods. 2018 Jun 17;: Authors: Bhupal PK, Anderson KA, Shall GP, Lynn JD, Hoolsema KS, Rossignol J, Dunbar GL, Sandstrom MI Abstract BACKGROUND: Putative treatments derived from in-vivo stem cell ... read more
- Sudlow Site II of Human Serum Albumin remains functional after Gold Nanocluster Encapsulation: a Fluorescence-Based Drug Binding Study of L-Dopa.Sudlow Site II of Human Serum Albumin remains functional after Gold Nanocluster Encapsulation: a Fluorescence-Based Drug Binding Study of L-Dopa. Methods Appl Fluoresc. 2018 Jun 20;: Authors: Russell BA, Garton A, Alshammari AS, Birch DJS, Chen Y Abstract Fluorescent protein-encapsulated gold nanoclusters (AuNCs) offer a non-toxic means of sensing and ... read more
- Crucial role of protein oligomerization in the pathogenesis of Alzheimer’s and Parkinson’s diseases.Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases. FEBS J. 2018 Jun 20;: Authors: Choi ML, Gandhi S Abstract Misfolding and aggregation of the proteins amyloid-β (Aβ), tau and alpha-synuclein (α-syn) is the predominant pathology underlying the neurodegenerative disorders, Alzheimer's and Parkinson's disease. Whilst end ... read more
- Unilateral acne after facial palsy.Unilateral acne after facial palsy. An Bras Dermatol. 2018 Jun;93(3):441-442 Authors: Sudy E, Urbina F Abstract We describe a case of unilateral acne which appeared after an episode of facial nerve palsy. An 18-year-old female patient presented with papules and pustules predominantly located on the side where the facial paralysis ... read more
- Cholinergic control of striatal neurons to modulate L-dopa-induced dyskinesias.Cholinergic control of striatal neurons to modulate L-dopa-induced dyskinesias. Eur J Neurosci. 2018 Jun 20;: Authors: Bordia T, Perez X Abstract L-dopa induced dyskinesias (LIDs) are a disabling motor complication of L-dopa therapy for Parkinson's disease (PD) management. Treatment options remain limited and the underlying network mechanisms remain unclear due ... read more
- [Outpatient establishment and initial management of treatment with intraduodenal levodopa-carbidopa infusion in advanced Parkinson’s disease].[Outpatient establishment and initial management of treatment with intraduodenal levodopa-carbidopa infusion in advanced Parkinson's disease]. Rev Neurol. 2018 Jul 01;67(1):1-5 Authors: Fernandez-Pajarin G, Ares-Pensado B, Sesar A, Iglesias-Canle J, Masa-Vazquez L, Castro A Abstract INTRODUCTION: Treatment with intraduodenal levodopa-carbidopa infusion is one of the three therapies currently available for advanced ... read more
- High frequency peripheral vibration decreases completion time on a number of motor tasks.Related ArticlesHigh frequency peripheral vibration decreases completion time on a number of motor tasks. Eur J Neurosci. 2018 Jun 20;: Authors: Macerollo A, Palmer C, Foltynie T, Korlipara P, Limousin P, Edwards M, Kilner JM Abstract A recent theoretical account of motor control proposes that modulation of afferent information plays ... read more
- Primary tissue for cellular brain repair in Parkinson’s disease: Promise, problems and the potential of biomaterials.Related ArticlesPrimary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials. Eur J Neurosci. 2018 Jun 20;: Authors: Moriarty N, Parish CL, Dowd E Abstract The dopamine precursor, levodopa, remains the 'gold-standard' treatment for Parkinson's disease, and, although it provides superlative efficacy in the ... read more
- Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson’s models.Related ArticlesAlpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models. Acta Neuropathol. 2018 Jun 09;: Authors: Shaltouki A, Hsieh CH, Kim MJ, Wang X Abstract Alpha-synuclein is a component of Lewy bodies, the pathological hallmark of Parkinson's disease (PD), and is also mutated in familial PD. Here, ... read more
- Technology-enabled management of communication and swallowing disorders in Parkinson’s disease: a systematic scoping review.Related ArticlesTechnology-enabled management of communication and swallowing disorders in Parkinson's disease: a systematic scoping review. Int J Lang Commun Disord. 2018 Jun 19;: Authors: Theodoros D, Aldridge D, Hill AJ, Russell T Abstract BACKGROUND: Communication and swallowing disorders are highly prevalent in people with Parkinson's disease (PD). Maintenance of functional ... read more
- Genomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinson’s gene.Related ArticlesGenomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinson's gene. Immunogenetics. 2018 Jun 19;: Authors: Saeed M Abstract Parkinson's disease (PD) is a common, disabling neurodegenerative disorder with significant genetic underpinnings. Multiple genome-wide association studies (GWAS) have been conducted with identification of several PD loci. However, ... read more
- Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers. Cell Rep. 2018 Jun 19;23(12):3492-3500 Authors: Whiten DR, Cox D, Horrocks MH, Taylor CG, De S, Flagmeier P, Tosatto L, Kumita JR, Ecroyd H, Dobson CM, Klenerman D, Wilson MR Abstract The aberrant aggregation of α-synuclein is associated ... read more
- Olfactory Function in SCA10.Related ArticlesOlfactory Function in SCA10. Cerebellum. 2018 Jun 19;: Authors: Moscovich M, Munhoz RP, Moro A, Raskin S, McFarland K, Ashizawa T, Teive HAG, Silveira-Moriyama L Abstract Although the main clinical manifestations of spinocerebellar ataxias (SCAs) result from damage of the cerebellum, other systems may also be involved. Olfactory deficits ... read more
- Toxic effects of Lambda-cyhalothrin, on the rat thyroid: Involvement of oxidative stress and ameliorative effect of ginger extract.Related ArticlesToxic effects of Lambda-cyhalothrin, on the rat thyroid: Involvement of oxidative stress and ameliorative effect of ginger extract. Toxicol Rep. 2018;5:728-736 Authors: Al-Amoudi WM Abstract Lambda-cyhalothrin (LCT) is a synthetic pyrethroid that is widely used to control insecticide. Ginger is a traditional plant that is widely used as a ... read more
- Peripheral T lymphocyte immunity and l-dopamine in patients with Parkinson’s disease.Related ArticlesPeripheral T lymphocyte immunity and l-dopamine in patients with Parkinson's disease. J Biol Regul Homeost Agents. 2018 May-Jun;32(3):687-691 Authors: Hu ZX, Song WN, Lu XD, Zhou ML, Shao JH Abstract This study aimed to evaluate the efficacy of T-cell immune function and L-dopamine (L-DOPA) in patients with Parkinson’s disease ... read more
- Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration.Related ArticlesPartial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration. Front Aging Neurosci. 2018;10:160 Authors: Yan A, Zhang Y, Lin J, Song L, Wang X, Liu Z Abstract Background: Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). ... read more
- Potential application of venom proteins in designing of medicines for treating human neurodegenerative disorders.Related ArticlesPotential application of venom proteins in designing of medicines for treating human neurodegenerative disorders. Protein Pept Lett. 2018 Jun 14;: Authors: Niazi ZR, Khan N, Khan S, Alam M, Kamal MA Abstract BACKGROUND: Neurodegenerative disorder are persistently increasing and relentlessly affecting the individuals, families and society as whole. Regrettably ... read more
- What would Dr. James Parkinson think today? parcelling out the circuitry of levodopa-induced dyskinesias.Related ArticlesWhat would Dr. James Parkinson think today? parcelling out the circuitry of levodopa-induced dyskinesias. Mov Disord. 2017 04;32(4):483-484 Authors: Kordower JH PMID: 28425143 [PubMed - indexed for MEDLINE] ... read more
- Directional local field potential recordings for symptom-specific optimization of deep brain stimulation.Related ArticlesDirectional local field potential recordings for symptom-specific optimization of deep brain stimulation. Mov Disord. 2017 04;32(4):626-628 Authors: Fernández-García C, Foffani G, Dileone M, Catalán-Alonso MJ, González-Hidalgo M, Barcía JA, Alonso-Frech F PMID: 28339118 [PubMed - indexed for MEDLINE] ... read more
- Adaptive deep brain stimulation controls levodopa-induced side effects in Parkinsonian patients.Related ArticlesAdaptive deep brain stimulation controls levodopa-induced side effects in Parkinsonian patients. Mov Disord. 2017 04;32(4):628-629 Authors: Rosa M, Arlotti M, Marceglia S, Cogiamanian F, Ardolino G, Fonzo AD, Lopiano L, Scelzo E, Merola A, Locatelli M, Rampini PM, Priori A PMID: 28211585 [PubMed - indexed for MEDLINE] ... read more
- A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils.A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils. Biophys J. 2018 Jun 19;114(12):2811-2819 Authors: Lv G, Kumar A, Huang Y, Eliezer D Abstract Fibrillar α-synuclein (AS) is the major component of Lewy bodies, the pathological hallmark of Parkinson's disease. Using solid-state nuclear magnetic resonance (ssNMR), we previously reported ... read more
- Therapeutic Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Neuroinflammation and Neuroplasticity in Patients with Parkinson’s Disease: a Placebo-Controlled Study.Related ArticlesTherapeutic Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Neuroinflammation and Neuroplasticity in Patients with Parkinson's Disease: a Placebo-Controlled Study. Bull Exp Biol Med. 2018 Jun 19;: Authors: Aftanas LI, Gevorgyan MM, Zhanaeva SY, Dzemidovich SS, Kulikova KI, Al'perina EL, Danilenko KV, Idova GV Abstract The parallel placebo-controlled study ... read more
- Magnesium in the Central Nervous SystemRelated ArticlesMagnesium in the Central Nervous System Book. 2011 Authors: Vink R, Nechifor M Abstract The cytosolic free magnesium concentration can be assessed in vivo in the human brain by phosphorus magnetic resonance spectroscopy. This technique has been employed in the human brain, providing new hints on the Mg2+ homeostasis ... read more