Parkinson’s Disease Latest Research

Related ArticlesSHARQnet - Sophisticated harmonic artifact reduction in quantitative susceptibility mapping using a deep convolutional neural network. Z Med Phys. 2019 Feb 14;: Authors: Bollmann S, Kristensen MH, Larsen MS, Olsen MV, Pedersen MJ, Østergaard LR, O'Brien K, Langkammer C, Fazlollahi A, Barth M Abstract Quantitative susceptibility mapping (QSM) reveals ... read more

Related ArticlesDevelopment of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease. Bioorg Med Chem Lett. 2019 Jan 30;: Authors: Lesuisse D, Malanda A, Peyronel JF, Evanno Y, Lardenois P, De-Peretti D, Abécassis PY, Barnéoud P, Brunel P, Burgevin MC, Cegarra C, ... read more

Related ArticlesParkinson's Disease Is Associated with Risk of Sexual Dysfunction in Men but Not in Women: A Systematic Review and Meta-Analysis. J Sex Med. 2019 Feb 14;: Authors: Zhao S, Wang J, Xie Q, Luo L, Zhu Z, Liu Y, Luo J, Zhao Z Abstract BACKGROUND: Mounting evidence has emerged ... read more

Related ArticlesClinical heterogeneity of frontotemporal dementia and Parkinsonism linked to chromosome 17 caused by MAPT N279K mutation in relation to tau positron emission tomography features. Mov Disord. 2019 Feb 17;: Authors: Ikeda A, Shimada H, Nishioka K, Takanashi M, Hayashida A, Li Y, Yoshino H, Funayama M, Ueno Y, Hatano ... read more

Related Articles[Progress of researches on acupuncture treatment of diseases by regulating endoplasmic reticulum stress]. Zhen Ci Yan Jiu. 2019 Jan 25;44(1):75-9 Authors: Zhao H, Jiang J Abstract Endoplasmic reticulum stress (ERS) is one of the major defense networks in mammals, but continuous ERS will lead to cell apoptosis, inducing initiation ... read more

Related ArticlesDiscovery of monoamine oxidase inhibitors by medicinal chemistry approaches. Medchemcomm. 2019 Jan 01;10(1):10-25 Authors: Hong R, Li X Abstract Neuropsychiatric disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD) and depression, have seriously inconvenienced the lives of patients. Growing evidence indicates that these diseases are closely related to the ... read more

Related ArticlesEffect of superparamagnetic nanoparticles coated with various electric charges on α-synuclein and β-amyloid proteins fibrillation process. Int J Nanomedicine. 2019;14:799-808 Authors: Javdani N, Rahpeyma SS, Ghasemi Y, Raheb J Abstract Background: Most of nanoparticles are nontoxic and have high absorption capability. Therefore, nanoparticles binding can effectively restrain fibrillation of ... read more

Related ArticlesMonitoring metal-amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening. Chem Sci. 2019 Jan 28;10(4):1000-1007 Authors: Lee HJ, Lee YG, Kang J, Yang SH, Kim JH, Ghisaidoobe ABT, Kang HJ, Lee SR, Lim MH, Chung SJ Abstract Aggregation of amyloidogenic peptides could cause the onset and progression ... read more

Related ArticlesConstipation, deficit in colon contractions and alpha-synuclein inclusions within the colon precede motor abnormalities and neurodegeneration in the central nervous system in a mouse model of alpha-synucleinopathy. Transl Neurodegener. 2019;8:5 Authors: Rota L, Pellegrini C, Benvenuti L, Antonioli L, Fornai M, Blandizzi C, Cattaneo A, Colla E Abstract Background: ... read more

Related ArticlesRole of immune-pineal axis in neurodegenerative diseases, unraveling novel hybrid dark hormone therapies. Heliyon. 2019 Jan;5(1):e01190 Authors: Beriwal N, Namgyal T, Sangay P, Al Quraan AM Abstract The anti-oxidant effects of melatonin and the immune-pineal axis are well established. However, how they play a role in the pathogenesis of ... read more

Related ArticlesConnectivity Between Brain Networks Dynamically Reflects Cognitive Status of Parkinson's Disease: A Longitudinal Study. J Alzheimers Dis. 2019;67(3):971-984 Authors: Klobušiaková P, Mareček R, Fousek J, Výtvarová E, Rektorová I Abstract BACKGROUND: Cognitive impairment in Parkinson's disease (PD) is associated with altered connectivity of the resting state networks (RSNs). Longitudinal ... read more

Related ArticlesComparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease. Mov Disord. 2019 Feb;34(2):285-291 Authors: Hendershott TR, Zhu D, Llanes S, Zabetian CP, Quinn J, Edwards KL, Leverenz JB, Montine T, Cholerton B, Poston KL Abstract BACKGROUND: Clinicians and researchers commonly use global cognitive assessments to ... read more

Related ArticlesA Palm-Worn Device to Quantify Rigidity in Parkinson's Disease. J Neurosci Methods. 2019 Feb 15;: Authors: Perera T, Lee WL, Jones M, Tan JL, Proud EL, Begg A, Sinclair NC, Peppard R, McDermott HJ Abstract BACKGROUND: Parkinsonian rigidity is identified on clinical examination as resistance to passive movement. Measurement ... read more

Related ArticlesConstruction of Parkinson's disease marker-based weighted protein-protein interaction network for prioritization of co-expressed genes. Gene. 2019 Feb 15;: Authors: George G, Snijesh VP, Lokappa SB, Varkey J Abstract BACKGROUND: Parkinson's disease (PD) is a complex neurodegenerative movement disorder that primarily results due to the loss of dopaminergic neurons in ... read more

Related ArticlesThe primary neuronal cells are more resistant than PC12 cells to α-synuclein toxic aggregates. Neurosci Lett. 2019 Feb 15;: Authors: Heravi M, Dargahi L, Parsafar S, Tayaranian Marvian A, Aliakbari F, Morshedi D Abstract BACKGROUND: Alpha-synuclein (αSN) is an abundant presynaptic brain protein that its aggregated species believed to ... read more

Related ArticlesDopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease. Cortex. 2019 Jan 29;115:99-111 Authors: Trujillo P, van Wouwe NC, Lin YC, Stark AJ, Petersen KJ, Kang H, Zald DH, Donahue MJ, Claassen DO Abstract Parkinson's disease (PD) is characterized by dysfunction in frontal cortical and ... read more

Continuing pharmacy education practices in geriatric care among pharmacists in the Upper Midwest. J Am Pharm Assoc (2003). 2019 Feb 13;: Authors: Marvanova M, Henkel PJ Abstract OBJECTIVES: To summarize select continuing pharmacy education (CPE) topics and hours related to geriatric care completed by community, hospital/clinic, and long-term care (LTC)/consultant ... read more

Development of evidence-based quality indicators for deep brain stimulation in patients with Parkinson's disease and first year experience of implementation of a nation-wide registry. Parkinsonism Relat Disord. 2019 Feb 05;: Authors: Haas K, Stangl S, Steigerwald F, Matthies C, Gruber D, Kühn AA, Krauss JK, Sixel-Döring F, von Eckardstein K, ... read more

General and abdominal adiposity and the risk of Parkinson's disease: A prospective cohort study. Parkinsonism Relat Disord. 2019 Feb 08;: Authors: Riso L, Kaaks R, Kühn T, Sookthai D, Forsgren L, Trupp M, Trichopoulou A, La Vecchia C, Karakatsani A, Gavrila D, Ferrari P, Freisling H, Petersson J, Lewan S, ... read more

Altered functional network topology correlates with clinical measures in very early-stage, drug-naïve Parkinson's disease. Parkinsonism Relat Disord. 2019 Feb 07;: Authors: Sreenivasan K, Mishra V, Bird C, Zhuang X, Yang Z, Cordes D, Walsh RR Abstract INTRODUCTION: The aim of the study was to identify abnormalities of whole-brain network functional ... read more

Parkinson's disease and pain: Modulation of nociceptive circuitry in a rat model of nigrostriatal lesion. Exp Neurol. 2019 Feb 14;: Authors: Domenici RA, Campos ACP, Maciel ST, Berzuino MB, Hernandes MS, Fonoff ET, Pagano RL Abstract Parkinson's disease (PD) is a neurodegenerative disorder that causes progressive dysfunction of dopaminergic and ... read more

Polysomnographic data in Dementia with Lewy Bodies: correlation with clinical symptoms and comparison with other α-synucleinopathies. Sleep Med. 2018 Dec 18;55:62-68 Authors: Bugalho P, Salavisa M, Marto JP, Borbinha C, Alves L Abstract INTRODUCTION: Sleep dysfunction is frequent in Dementia with Lewy Bodies (DLB), but polysomnographic (PSG) data is scarce. ... read more

Deep brain stimulation of the subthalamic nucleus in Parkinson's disease patients over 75 years of age. J Neurol Sci. 2019 Feb 11;399:57-60 Authors: Sharma VD, Lyons KE, Nazzaro JM, Pahwa R Abstract INTRODUCTION: Deep brain stimulation (DBS) is an effective therapy for Parkinson's disease (PD). However, its effect in older patients ... read more

Detection of REM sleep behaviour disorder by automated polysomnography analysis. Clin Neurophysiol. 2019 Feb 06;130(4):505-514 Authors: Cooray N, Andreotti F, Lo C, Symmonds M, Hu MTM, De Vos M Abstract OBJECTIVE: Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a ... read more

A rare cause of axial worsening in Parkinson's disease: A case of myasthenic pseudo-parkinsonism. Clin Neurol Neurosurg. 2019 Feb 11;179:1-3 Authors: Marano M, Lanzone J, di Biase L, Pepe A, Di Santo A, Di Lazzaro V PMID: 30772769 [PubMed - as supplied by publisher] ... read more