Parkinson’s Research News

Newsfeed:

  • Dementia: How to Prevent Cognitive Decline
    Identifying the optimal number of individual treatment sessions for those with cognitive decline associated with dementia is crucial for managing the neurodegenerative disease. ... read more
    Source: Neuro Science NewsPublished on 2022-01-20By Neuroscience News
  • Cholesterol Buildup in Brain Presents New Target to Reduce Dementia Risk From Stroke
    Cyclodextrin, an FDA-approved drug, reduced cholesterol accumulation from broken down brain cells and inflammation in animal models. The findings point to a potential new therapy to reduce dementia following a stroke. ... read more
    Source: Neuro Science NewsPublished on 2022-01-19By Neuroscience News
  • New Screening Tool Developed to Automatically Identify Older Appearing Brains Typical of Dementia
    A new artificial intelligence algorithm analyses MRI data to accurately predict the age of a brain. ... read more
    Source: Neuro Science NewsPublished on 2022-01-14By Neuroscience News
  • Inflammatory Markers Are Conspicuous During an Early Stage of Alzheimer’s
    Proteins belonging to the TAM family receptors may be a new biomarker for Alzheimer's disease. The elevated inflammatory markers are conspicuous, even before the onset of dementia. ... read more
    Source: Neuro Science NewsPublished on 2022-01-12By Neuroscience News
  • Get moving to put the brakes on early Parkinson’s
    A new study suggests that people with early-stage Parkinson's disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily activities later. ... read more
    Source: Science DailyPublished on 2022-01-12
  • New knowledge about the ‘happiness hormone’ dopamine
    New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's. ... read more
    Source: Science DailyPublished on 2022-01-11
  • Year in review: 2021
    # # # # As with the preceding year, 2021 proved to be challenging due to the continuing COVID-19 pandemic (and it is not over yet). Vaccines were rolled out with remarkable speed, but equally new variants of the virus popped up and have kept Governments and health regulatory bodies on their toes. An amazing feature of the ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-31By Simon
  • Monthly Research Review – December 2021
    # # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during December 2021. The post is divided into 10 parts ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-31By Simon
  • Parkinson’s protein blueprint could help fast-track new treatments
    Researchers have solved a decade-long mystery about a critical protein linked to Parkinson's disease that could help to fast-track treatments for the incurable disease. The research has produced a 'live action' view of the protein, called PINK1, in exquisite molecular detail. The discovery explains how the protein is activated in the cell, where it is responsible for initiating the removal ... read more
    Source: Science DailyPublished on 2021-12-23
  • Alzheimer’s Disease and the Holidays
    Researchers discuss how to accommodate family members with dementia over the holidays to make Christmas a meaningful and joyous event for the entire family. ... read more
    Source: Neuro Science NewsPublished on 2021-12-18By Neuroscience News
  • Parkinson’s Disease Mutation Misdirects Iron in the Brain
    Findings reveal a common Parkinson's disease genetic mutation drives mislocalization of iron in activated microglia. ... read more
    Source: Neuro Science NewsPublished on 2021-12-16By Neuroscience News
  • Parkinson’s disease mutation misdirects iron in the brain
    A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study. The results may help explain the accumulation of toxic iron in affected brain areas in the disease and provide a basis for the development of therapies designed to correct the iron trafficking defect. ... read more
    Source: Science DailyPublished on 2021-12-16
  • The terazosin pilot study results
    # # # # Drug repurposing represents a means of rapidly testing and bring novel therapies to the patient. By testing clinically available drugs – that have well characterised safety records in a particular medical condition – one can determine if a certain biological pathway is playing an influential role in another disease. A good example of this ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-15By Simon
  • COVID Protein Interacts With Parkinson’s Protein, Promotes Amyloid Formation
    The COVID causing SARS-CoV-2 protein interacts with alpha-synuclein, speeding up the formation of amyloid plaques, a new study reports. ... read more
    Source: Neuro Science NewsPublished on 2021-12-14By Neuroscience News
  • SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds
    Researchers have shown that, at least in the test tube, the SARS-CoV-2 N-protein interacts with a neuronal protein called alpha-synuclein and speeds the formation of amyloid fibrils, pathological protein bundles that have been implicated in Parkinson's disease. ... read more
    Source: Science DailyPublished on 2021-12-14
  • Slow-wave sleep saves synucleinopathy?
      # # # # Good sleep patterns have important implications for all of us in terms of health and well being, but sleep is often disrupted for people with Parkinson’s. Research suggests that people with Parkinson’s have reduced amounts of slow wave and REM sleep, and increased periods of wakefulness. A new report has found that ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-11By Simon
  • Are Scientists Homing in on a Cure for Parkinson’s Disease?
    Researchers have refined a molecule that shows promise for the prevention of Parkinson's disease. ... read more
    Source: Neuro Science NewsPublished on 2021-12-09By Neuroscience News
  • Are scientists homing in on a cure for Parkinson’s disease?
    A peptide known to prevent the protein error that gives rise to Parkinson's disease has been optimized by scientists. The new peptide is a strong candidate for future development into a cure. ... read more
    Source: Science DailyPublished on 2021-12-09
  • From wearable to invisibles
    # # # # New technologies that can help us to better understand and track Parkinson’s over time has been a theme here on the SoPD. Such tools could create fantastic opportunities, particularly in the context of clinical trials evaluating new therapies, by providing comparable quantitative measures. Many of these efforts have focused on wearable technologies that require ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-08By Simon
  • Fatty Acid Length Predicts Parkinson’s Disease Risk
    Chains of fatty acids in the lysosome that are one-half nanometer longer than normal-length chains were associated with a degenerative form of Gaucher disease, a genetic condition related to Parkinson's disease. ... read more
    Source: Neuro Science NewsPublished on 2021-12-08By Neuroscience News
  • Self-Administered Cognition Test Predicts Early Signs of Dementia Sooner
    A newly developed self-assessment test of cognitive function can help detect early signs of dementia sooner than commonly used office-based cognitive tests. ... read more
    Source: Neuro Science NewsPublished on 2021-12-07By Neuroscience News
  • ADepTing to the UCB-Novartis deal
    # # # # Alpha synuclein has long been viewed at “Public enemy #1” by the Parkinson’s research community. This sticky, abundant protein starts to cluster (or aggregate) in Parkinson’s. There have been several attempts to reduce levels of the protein floating around outside of cells (using “immunotherapy” approaches) But now clinical research is ramping up to determine ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-06By Simon
  • Cataract Surgery Linked With Lessened Dementia Risk
    Cataract surgery was associated with a 30% reduction in dementia risk for older adults, a new study reports. ... read more
    Source: Neuro Science NewsPublished on 2021-12-06By Neuroscience News
  • Elevated Heart Rate Linked to Increased Risk of Dementia
    Older people who experience elevated heart rates are at increased risk for developing dementia, researchers report. ... read more
    Source: Neuro Science NewsPublished on 2021-12-04By Neuroscience News
  • Getting a handle on Miro1
    # # # # Novel therapeutic interventions are being proposed for Parkinson’s on a regular basis, with compelling data supporting their future development. The case is strengthened when a measure of target engagement is also involved – providing not only a potential therapy but also a biomarker as well. Recently, a biotech company called AcureX Therapeutics has been ... read more
    Source: The Science of Parkinson’s diseasePublished on 2021-12-03By Simon
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