PD Research News

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  • Modified protein can prevent Alzheimer’s disease in mice
    Researchers injected a modified segment of the amyloid precursor protein into mouse models of Alzheimer's disease. The treatment appeared to reverse a number of the cognitive and memory problems associated with the neurodegenerative disease. ... read more
    Source: Neuro Science NewsPublished on 2019-06-14By Neuroscience News
  • Moral emotions, a diagnostic tool for frontotemporal dementia?
    Moral emotions are significantly more impaired than emotions without moral content in those with frontotemporal dementia (FTD). By contrast, those with Alzheimer's disease exhibit similar performance in both moral and extra-moral emotions as healthy subjects. The findings provide a novel biomarker for the diagnosis of FTD. ... read more
    Source: Neuro Science NewsPublished on 2019-06-14By Neuroscience News
  • Gut Bacteria Interferes with Metabolism of Parkinson’s Drug
    Study provides first concrete examples of how the microbiome can interfere with a drug's intended path throughout the body. ... read more
    Source: Neuro Science NewsPublished on 2019-06-13By Neuroscience News
  • Education and intelligence may protect cognition’ but don’t prevent Alzheimer’s disease
    Intelligence, education and participating in cognitively challenging tasks may stave off the effects of dementia for longer, but can not protect against the inevitable Alzheimer's pathology in those at risk. ... read more
    Source: Neuro Science NewsPublished on 2019-06-11By Neuroscience News
  • How ultrasound could help curb Parkinson’s
    Mouse study shows that focused ultrasound and injected microbubbles can help curb early Parkinson's disease by allowing drugs to access the brain. ... read more
    Source: Medical News DailyPublished on 2019-06-10
  • Parkinson’s: New gene therapy shows promise for prevention
    Researchers from Japan have tested a new gene therapy against Parkinson's disease using mouse models. Their results suggest that the approach is effective. ... read more
    Source: Medical News DailyPublished on 2019-06-07
  • Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages
    Using transcranial focused ultrasound in combination with injectable microbubbles, researchers open a pathway through the blood-brain barrier. The technique allows drugs to penetrate the brain and trigger therapeutic effects for those with neurodegenerative diseases. ... read more
    Source: Neuro Science NewsPublished on 2019-06-06By Neuroscience News
  • Scientists recreate blood-brain barrier defect outside the body
    Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips. ... read more
    Source: Neuro Science NewsPublished on 2019-06-06By Neuroscience News
  • Breaking down pathological protein aggregates
    Researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson's and other neurodegenerative diseases. ... read more
    Source: Science DailyPublished on 2019-06-06
  • Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages
    Researchers have developed a technique that could open up new ways to facilitate targeted drug delivery into the brain, enabling drugs to treat brain diseases more focally. They used transcranial, focused ultrasound and intravenously injected microbubbles into the blood-brain barrier (BBB) to make a localized, transient opening that allows drugs to cross through the BBB reversibly and noninvasively. ... read more
    Source: Science DailyPublished on 2019-06-06
  • Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages
    (Columbia University School of Engineering and Applied Science) Researchers have developed a technique that could open up new ways to facilitate targeted drug delivery into the brain, enabling drugs to treat brain diseases more focally. They used transcranial, focused ultrasound and intravenously injected microbubbles into the blood-brain barrier (BBB) to make a localized, transient opening that allows drugs to cross ... read more
    Source: Eureka AlertPublished on 2019-06-06
  • Breaking down pathological protein aggregates
    (ETH Zurich) ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson's and other neurodegenerative diseases. This new finding might provide the basis for new therapeutic approaches. ... read more
    Source: Eureka AlertPublished on 2019-06-06
  • WPC 2019 – Day 1
      This post provides an overview of activities on Day 1 at the World Parkinson’s Congress meeting in Kyoto. After a spectacular opening ceremony the night before, Day 1 began with some impressive keynote presentations. Then came a series of fascinating workshops and roundtables before ... read more
    Source: The Science of Parkinson’s diseasePublished on 2019-06-05By Simon
  • Stopping Parkinson’s disease before it starts
    (Osaka University) Parkinson's disease (PD) is a progressive neurodegenerative disease affecting millions of people worldwide. Characterized by accumulation of the protein α-synuclein, there is currently no cure for PD. In a new study published this month in Scientific Reports, a research team led by Osaka University designed small fragments of DNA that bind to α-synuclein mRNA, preventing it from being ... read more
    Source: Eureka AlertPublished on 2019-06-05
  • Tel Aviv University researchers spearhead early detection of Parkinson’s disease
    (American Friends of Tel Aviv University) New research from Tel Aviv University may lead to the early detection of Parkinson's disease, which can lead to treatment that has the potential to significantly delay the progression of the disease. ... read more
    Source: Eureka AlertPublished on 2019-06-05
  • Promising molecule targets protein to offer hope for people with Parkinson’s
    (Parkinson's UK) Results from a study published today looking at a molecule targeting clumps of alpha-synuclein, a key protein linked to Parkinson's, offers hope that it may be possible to slow down or prevent the progression of the condition in humans. ... read more
    Source: Eureka AlertPublished on 2019-06-05
  • WPC 2019 – Day 0
      Every three years the Parkinson’s community – patients, families, researchers, and clinicians – comes together to learn from each other, discuss where we are, and explore where we should be going. The World Parkinson’s Congress (or WPC) is a very special event – rather ... read more
    Source: The Science of Parkinson’s diseasePublished on 2019-06-04By Simon
  • Brush your teeth to postpone Alzheimer’s
    Brushing your teeth may be a way to stave off the development of Alzheimer's disease. Study provides new evidence of how bacteria associated with gingivitis contributes to the development of the neurodegenerative disease. ... read more
    Source: Neuro Science NewsPublished on 2019-06-03By Neuroscience News
  • Could a Mediterranean diet and exercise reduce dementia risk?
    A new study will investigate the effects of exercise and eating a Mediterranean style diet has on the development of dementia, and whether a change in lifestyle has neuroprotective properties. Researchers are looking for volunteers between 55 and 74 years of age to participate in the study. ... read more
    Source: Neuro Science NewsPublished on 2019-06-02By Neuroscience News
  • Monthly Research Review – May 2019
      At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during May 2019. The post is divided into seven parts based on the type of research: ... read more
    Source: The Science of Parkinson’s diseasePublished on 2019-05-31By Simon
  • Remembering Tom
      On 31st May in 2017, Tom Isaacs – one of the co-founder of the the Cure Parkinson’s Trust – passed away suddenly. It was a terrible shock for the Parkinson’s community, many of whom saw Tom as a leader of advocacy efforts. In today’s ... read more
    Source: The Science of Parkinson’s diseasePublished on 2019-05-30By Simon
  • NIH awards Cleveland Clinic $3 million grant to determine effects of exercise in Parkinson’s
    (Cleveland Clinic) The National Institutes of Health has awarded Cleveland Clinic researcher Jay Alberts, Ph.D, a 5-year, $3 million grant to conduct a multi-site clinical trial to study the long-term effects of aerobic exercise on slowing the progression of Parkinson's disease. ... read more
    Source: Eureka AlertPublished on 2019-05-29
  • As plaque deposits increase in the aging brain, money management falters
    Older adults who experience problems completing simple financial tasks, such as calculating their change, may be at increased risk of Alzheimer's disease. Problems with financial management have often been associated with later stage dementia. A new study reveals this could be one of the earliest signs of dementia and may be correlated with a build-up of amyloid plaque deposits. ... read more
    Source: Neuro Science NewsPublished on 2019-05-28By Neuroscience News
  • Newly discovered mechanism reveals how Parkinson’s disease can spread between brain cells
    Connexins play a critical role in the uptake and transfer of Parkinson's related proteins from one cell to another. The findings may help with the development of new treatments for Parkinson's disease. ... read more
    Source: Neuro Science NewsPublished on 2019-05-28By Neuroscience News
  • Newly discovered mechanism reveals how Parkinson’s disease can spread between brain cells
    Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson's disease can spread throughout the brain, according to new research from Linköping University, Sweden. The results demonstrate that harmful protein aggregates, or deposits, can bind and 'hitch a lift' with channel-forming proteins, and in this way spread to healthy cells. The study has been published ... read more
    Source: Science DailyPublished on 2019-05-28
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