Parkinson’s Disease Research News

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  • Parkinson’s: Targeting new compound slows disease in rats
    The results of a decade-long study are in: a new therapeutic target is found, and scientists manage to slow the progression of the disease in animals. ... read more
    Source: Medical News DailyPublished on 2018-04-22
  • Concussion May Increase Parkinson’s Risk
    A new study reveals veterans who suffered a concussion are at a 56% increased risk of developing Parkinson's disease. ... read more
    Source: Neuro Science NewsPublished on 2018-04-19By Neuroscience News
  • A single concussion may increase risk of Parkinson’s disease
    People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson's disease. ... read more
    Source: Science DailyPublished on 2018-04-18
  • Ibudilast: A Phosphodiesterase inhibitor
    A reader recently asked me about an experimental drug called Ibudilast. It is a ‘Phosphodiesterase 4 inhibitor’. Recently there was a very interesting result in a clinical trial looking at Ibudilast in a specific neurodegenerative condition. Sadly for the reader that condition was not Parkinson’s, in fact ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-04-17By Simon
  • ALS: How ‘toxic’ proteins could protect neurons
    Researchers have found that large, fibrous aggregates thought to drive Lou Gehrig's disease might actually help to protect motor neurons. ... read more
    Source: Medical News DailyPublished on 2018-04-17
  • UDCA 2.0 = TUDCA?
    Ursodeoxycholic acid (UDCA) has been proposed as a drug that could be repurposed for Parkinson’s. As a medication, it is called ‘Ursodiol‘ and it is used to treat gallstones. But there are absorption issues with UDCA: The passage of UDCA through the wall of the small intestine is slow and ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-04-16By Simon
  • Americans with a College Education Live Longer Without Dementia
    Two new studies from researchers at USC provide fresh insight into Alzheimer's risks. Researchers say attending college can stave off dementia and help retain memories in old age. Additionally, researchers report reducing diabetes and hypertension after 50 could increase longevity in people with Alzheimer's disease. ... read more
    Source: Neuro Science NewsPublished on 2018-04-16By Neuroscience News
  • Immunological Memory in the Brain
    Researchers report inflammation reactions can cause long term alterations to immune cells in the brain which can influence the progression of neurodegenerative disorders later in life. ... read more
    Source: Neuro Science NewsPublished on 2018-04-11By Neuroscience News
  • The Brain Combats Dementia By Shifting Resources
    A new study reveals the brain may reassign tasks to different regions of the brain in order to counter the onset of neurodegenerative diseases. ... read more
    Source: Neuro Science NewsPublished on 2018-04-11By Neuroscience News
  • Study Confirms Link Between TBI and Dementia
    A new, large scale study reveals people who have experienced a traumatic brain injury have a significantly increased risk of developing dementia than those without a history of TBI. ... read more
    Source: Neuro Science NewsPublished on 2018-04-10By Neuroscience News
  • Discovery Sheds Light on How Neurodegenerative Diseases May Occur
    Researchers report nitric oxide plays a key role in regulating neural function. The findings shed new light on how neurodegeneration may occur. ... read more
    Source: Neuro Science NewsPublished on 2018-04-10By Neuroscience News
  • ALS and FTD Share Genetic Link
    A new study links common genetic variants to both ALS and frontotemporal dementia. The findings could help in the development of treatment strategies for both disorders, researchers report. ... read more
    Source: Neuro Science NewsPublished on 2018-04-09By Neuroscience News
  • Antiepileptic Drugs Increase Risk of Alzheimer’s
    A new study reveals antiepileptic drugs with side effects of impairing cognitive function can increase the risk of patients developing dementia and Alzheimer's disease. Additionally, the higher the dose of the medication used, the greater the risk of developing dementia, researchers report. ... read more
    Source: Neuro Science NewsPublished on 2018-04-09By Neuroscience News
  • The aggregating antics of (some) anaesthetics
    This is one of those posts that I am reluctant to write because there is the very real possibility of it being taken out of context and causing someone to panic. But several readers have asked me to address a new piece of research that was published this ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-04-07By Simon
  • Smartphone ‘scores’ can help doctors track severity of Parkinson’s disease symptoms
    (Johns Hopkins University) A new smartphone app allows Parkinson's disease patients and their doctors to better track the progression of symptoms, such as tremors and walking difficulties, that can vary dramatically over days, or even hours. ... read more
    Source: Eureka AlertPublished on 2018-04-06
  • Is there NOP hope for Parkinson’s?
    Please do not misread the title of this post! Compounds targeting the Nociceptin receptor (or NOP) could provide the Parkinson’s community with novel treatment options in the not-too-distant future. In pre-clinical models of Parkinson’s, compounds designed to block NOP have demonstrated neuroprotective properties, while drugs that stimulate NOP appear to ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-04-04By Simon
  • Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons
    Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells ... read more
    Source: Science DailyPublished on 2018-04-04
  • Nanoparticles may cause DNA damage to brain cells across a cellular barrier
    (Trinity College Dublin) New research by scientists shows that when cellular barriers are exposed to metal nanoparticles, cellular messengers are released that may cause damage to the DNA of developing brain cells. The discovery may have implications for the development of potential drug targets in the treatment of neurodegenerative conditions, ... read more
    Source: Eureka AlertPublished on 2018-04-04
  • Parkinson’s Disease and Binge Eating
    A new study sheds light on why some people with Parkinson's disease binge eat. Researchers report working memory impairment and alterations in reward sensitivity could be behind why binge eating can be problematic in those with Parkinson's. ... read more
    Source: Neuro Science NewsPublished on 2018-04-03By Neuroscience News
  • Cell discovery could help with research on genetic diseases
    (University of Kent) Cell discovery could help with research on genetic diseases Research carried out by the University of Kent has discovered the first data on an organelle that is really important in human cells in an ancient organism distantly related to humans.The discovery will enable scientists to study the ... read more
    Source: Eureka AlertPublished on 2018-04-03
  • Novel PET imaging agent could help guide therapy for brain diseases
    (Society of Nuclear Medicine and Molecular Imaging) Researchers have developed a new PET imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. The agent targets receptors in nerve cells in the brain that are involved in learning and ... read more
    Source: Eureka AlertPublished on 2018-04-02
  • Monthly Research Review – March 2018
    At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during March 2018. The post is divided into four parts based on the type of research (Basic biology, disease mechanism, ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-03-31By Simon
  • Objective measures: Getting smart about pills
    There has been a lot of discussion on this site (and elsewhere on the web) regarding the need for more objective systems of measuring Parkinson’s – particularly in the setting of clinical trials. Yes, subjective reports of patient experience are important, but they can easily be biased by ... read more
    Source: The Science of Parkinson’s diseasePublished on 2018-03-30By Simon
  • Researchers find ways to impede progress of neurodegenerative diseases
    (Kazan Federal University) As the paper posits, there is currently no doubt that hyperpolarization of mitochondria and concomitant oxidative stress are associated with the development of serious pathologies, such as Parkinson's disease, Alzheimer's disease, autoimmune syndromes, some cancers, and other conditions. Hyperpolarized mitochondria have an elevated transmembrane potential because of ... read more
    Source: Eureka AlertPublished on 2018-03-30
  • Sensors to prevent Parkinson’s patients from falling
    (University of Erlangen-Nuremberg) A groundbreaking project for Parkinson's patients from the European Institute of Innovation and Technology Health (EIT Health) titled 'MoveIT' has now been launched under the lead of the Molecular-Neurological Department at Universitätsklinikum Erlangen in collaboration with researchers from Friedrich-Alexander-Universität Erlangen-Nürnberg and other European partners. Using telemedicine based ... read more
    Source: Eureka AlertPublished on 2018-03-28
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