Parkinson’s Research News

A subtle increase of the PKCα protein produces biochemical, cellular, and cognitive impairments akin to those seen in Alzheimer's disease. The finding provides a potential new target for the treatment of the neurodegenerative disorder. ... read more

Researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson's patients. These could be used in the future as a new type of biomarker for this disease. ... read more

Previous TBI increased the risk of frontotemporal dementia in those without a genetic risk factor for FTD. Additionally, researchers found those with FTD tend to be less educated than those with Alzheimer's disease. ... read more

The shape of a specific set of proteins differs in the spinal fluid of patients with Parkinson's disease compared to those without the neurodegenerative disease. ... read more

Krill oil protects dopaminergic neurons from age-related degeneration, decreases alpha-synuclein aggregation, and improves dopamine-dependent cognition and behavior in lab models of Parkinson's disease. ... read more

A novel compound eliminates disease-causing segments of RNA associated with ALS and dementia, and restores the health of neurons in mouse models. ... read more

Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD. ... read more

Water plays a key role in how proteins associated with Parkinson's disease fold, clump or misfold. ... read more

Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer's. ... read more

A newly developed brain atlas could help with the study and diagnosis of mental health and neurodegenerative disorders by correlating brain networks with underlying anatomical structures. ... read more

A team has developed a new tool that can predict how Parkinson's disease patients will fare over the course of a year based on their genetics, brain scans and physical examinations. ... read more

Researchers have discovered that the neurotransmitter adenosine effectively acts as a brake to dopamine, another well-known neurotransmitter involved in motor control. The discovery could immediately suggest new avenues of drug development to treat symptoms of Parkinson's disease, a movement disorder where the loss of dopamine-producing cells has been widely implicated as a cause. ... read more

CPAP treatments for sleep apnea have the potential to reduce dementia risk, a new study reports. ... read more

Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the rest of all Parkison's cases, the disease begins before 40 years old. Now, a group of researchers has deciphered the molecular mechanism by which a mutation of the adenosine type 1 receptor gene is associated with ... read more

Musical memories are often preserved in those with Alzheimer's disease. Researchers say listening to music can have a positive impact on emotion and behavior for those with Alzheimer's and other forms of dementia. ... read more

Of patients with dementia, 7% had chronic kidney disease while 9% had albuminuria, a urinary marker for kidney disease. Chronic kidney disease was associated with a 51% increased risk of developing dementia. ... read more

Deletion of the neurodegenerative disease associated microglial gene CX3CR1 aggravated the disease state and increased the accumulation of plaques in the brains of mouse models of Alzheimer's disease. Deficiencies of the gene also impaired the movement of microglia toward the plaques. ... read more

A new treatment for neurological and psychiatric diseases, that works by reducing the excitability of overactive brain cells, has been developed. ... read more

COVID-19 infection activates the same inflammatory response in the brain as Parkinson's disease, a new study reports. ... read more

Researchers have found that COVID-19 activates the same inflammatory response in the brain as Parkinson's disease. The discovery identified a potential future risk for neurodegenerative conditions in people who've had COVID-19, but also a possible treatment. ... read more

SGDGs, a class of lipids that decline in the brain during aging, appear to have anti-inflammatory effects that could have implications for neurodegenerative disorders. ... read more

A genetic form of frontotemporal dementia is associated with abnormal lipid accumulation in the brain fueled by disrupted cell metabolism. The findings could pave the way for new targeted therapies for FTD. ... read more

The Chlamydia pneumoniae bacteria can travel directly from olfactory nerve in the nose and into the brain, forcing brain cells to deposit amyloid beta and inducing Alzheimer's pathologies. Researchers say protecting the lining of the nose by not picking or plucking nasal hairs can help lower Alzheimer's risks. ... read more

Results imply a linear relationship between blood pressure reduction and lower dementia risk in adults aged 69 and older. ... read more

A new study reveals that 10% of adults over the age of 65 in the USA have dementia, while another 22% suffer from mild cognitive impairment. ... read more