Newsfeed:
- Protecting the Brain From Dementia-Inducing Abnormal Protein AggregatesResearchers reveal the critical role the p62 gene plays in the selective autophagy of tau oligomers. ... read more
- New DNA Clues for Parkinson’s Disease RiskAlterations in the nascent transcription of introns may indicate risk factors for, and the progression of Parkinson's disease. ... read more
- Socially Isolated People Have Differently Wired Brains and Poorer CognitionSocial isolation is linked to alterations in brain structure and cognitive deficits. Additionally, social isolation can increase the risk of developing dementia as a person ages. ... read more
- Willingness to Give Away Money Among Older Adults Linked to Cognitive Profile of Early Alzheimer’sWillingness in older people to give more money away appears to correlate with cognitive decline associated with dementia. The findings may explain why many older adults could be more prone to financial exploitation. ... read more
- Diabetes and Cardiovascular Disease Increase Dementia RiskPeople with two of the diseases, type 2 diabetes, cardiovascular disease or stroke have double the risk of developing dementia, researchers say. ... read more
- Vitamin D Deficiency Leads to DementiaResearchers found an association between low vitamin D levels and reduced brain volume. Lower vitamin D was also linked to an increased risk of stroke and dementia. Up to 17% of dementia cases could be prevented by increasing vitamin D. ... read more
- High Prevalence of Recently Defined Non-Alzheimer’s DementiaThe prevalence of brain changes associated with LATE, a form of dementia first identified in 2019, may be as high as 40% in older adults and 50% in those with Alzheimer's disease. ... read more
- A New Candidate Therapeutic Target for Parkinson’s Disease IdentifiedResearchers identified LIPE, a lipase that degrades triglycerides to produce fatty acids, as a potential new target for the development of treatments for Parkinson's disease. ... read more
- Multiple Heart-Related Conditions Linked to Triple Dementia Risk, Regardless of GeneticsPeople who suffer cardiometabolic disorders, such as stroke, diabetes, or a heart attack, either as stand-alone conditions or a combination of the conditions, have an increased risk of developing dementia regardless of whether or not they have a genetic predisposition for neurodegeneration. ... read more
- Does Shingles Increase a Person’s Risk of Dementia?Despite speculation that inflammation associated with the shingles virus can increase dementia risk, researchers found little evidence to substantiate the claim. ... read more
- People With a High Omega-3 DHA Level in Their Blood Are at 49% Lower Risk of Alzheimer’sPeople with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia. ... read more
- A ‘Double Life’ for a Key Parkinson’s Disease ProteinThe Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease. ... read more
- Social Isolation Is Directly Associated With Later DementiaSocial isolation has been directly linked to structural changes in brain areas associated with memory and cognitive function. Researchers report socially isolated people are 26% more likely to develop dementia later in life. ... read more
- Bad Dreams Could Be Early Warning of Parkinson’s DiseaseOlder adults who frequently experience bad dreams or nightmares are twice as likely to be diagnosed with Parkinson's disease, a new study reports. ... read more
- Three Distinct Brain Circuits in the Thalamus Contribute to Parkinson’s SymptomsNeurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease. ... read more
- Three distinct brain circuits in the thalamus contribute to Parkinson’s symptomsNeuroscientists identified three circuits in the thalamus that influence the development of motor and nonmotor symptoms of Parkinson's disease. And by manipulating these circuits, they could reverse Parkinson's symptoms in mice. ... read more
- Bad dreams could be early warning of Parkinson’s diseaseOlder adults who start to experience bad dreams or nightmares could be exhibiting the earliest signs of Parkinson's disease, say researchers. ... read more
- Finding a talisman# # # # Experiential observations and anecdotal insights from the patient community have generated many key discoveries for the field of Parkinson’s research. A chance question (“Why do people with Parkinson’s smell different?” – click here to read more about that) or random interaction have opened doors to entirely new realms of research. An good example of ... read more
- Brain Wave Sleep Data Can Predict Future Health OutcomesBrain wave data collected during sleep predicts the future incidences of 11 health-related outcomes, including dementia, cardiovascular health, psychological disorders, and mortality. ... read more
- You’ve Likely Heard of the Brain’s Gray Matter – Here’s Why the White Matter Is Important TooWhite matter may be the key to understanding dementia, TBI, and numerous other neurological disorders. ... read more
- Increased Risk of Dementia and Depression in Rheumatoid ArthritisPeople suffering from rheumatoid arthritis are 1.2 times more likely to develop depression. Additionally, the risk of developing dementia increased by 2-3% every 5 years following a diagnosis of RA. ... read more
- Overlooked Proteins May Be Key to Better Diagnosis of Alzheimer’sFragmented tau that accumulates in neurons in those with Alzheimer's disease may be a new target for drugs to treat the neurodegenerative disease. ... read more
- Stretchable Probe Measures Brain Chemicals Central to Parkinson’s, Depression, and Gut DiseaseA newly invented soft, implantable probe can interface between gut and brain tissue, measuring both dopamine and serotonin levels. The device has applications for depression, Parkinson's disease, and intestinal disorders. ... read more
- Monthly Research Review – May 2022
# # # # At the end of each month the SoPD writes a post which provides an overview of some of the major pieces of Parkinson’s-related research that were made available during May 2022. The post is divided into 10 parts ... read more
- How Cranberries Could Improve Memory and Ward off DementiaOlder adults who consumed cranberries frequently as part of their diet saw improvements in episodic memory, neural function, and brain perfusion. Cranberry consumption was also linked to a significant decrease in LDL cholesterol. Findings reveal adding cranberries to the diet helps to improve memory and could protect against dementia. ... read more