Beyond Dopamine - Does PD Effect Other Neurotransmitters?

Beyond Dopamine – Does PD Effect Other Neurotransmitters?

Trends in PD research are showing that in addition to Parkinson’s impact on the neurotransmitter dopamine and the dopamingeric system, the neurotransmitter acetylcholine and the brain’s cholingeric system are also impacted. This post reviews recent research (and some very old research that may need to be revisited), and discusses how two vitamins/supplements (Vitamin B12 and Citicoline/CDP Choline) may impact Parkinson’s disease. This should not be considered medical advice. Always consult your doctors and pharmacist about any vitamins or supplements that you are taking or considering. Related: Exhibit A: Yale Study challenges assumptions about PD and acetylcholine Several weeks ago, a ...
Beyond l-dopa for PD gait disturbances, balance issues and falls - CDP Choline?

Beyond l-dopa for PD gait disturbances, balance issues and falls – CDP Choline?

A study published this week raises an interesting point: Mobility deficits, including gait disturbance, balance impairments and falls, are common features of Parkinson's disease (PD) that negatively impact quality of life. Mobility deficits respond poorly to dopaminergic medications, indicating a role for additional neurotransmitters. Due to the critical role of cortical input to gait and balance, acetylcholine-an essential neurotransmitter system for attention-has become an area of interest for mobility. Overview of the cholinergic contribution to gait, balance and falls in Parkinson's disease I find this interesting, because the first Movement Disorder Specialist that I met with to confirm my Parknson’s ...